Publications

Publications of Members of the Institute for Modelling and Simulation of Biomechanical Systems

International, peer-reviewed Publications

2021
1. Bleiler, C., Ponte Castañeda, P., & Röhrle, O. (2021). Tangent second-order homogenisation estimates for incompressible hyperelastic composites with fibrous microstructures and anisotropic phases. Journal of the Mechanics and Physics of Solids, 147, 104251. https://doi.org/10.1016/j.jmps.2020.104251
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  @article{Bleiler2021, author = {Bleiler, Christian and Ponte Casta{\~{n}}eda, Pedro and R{\"o}hrle, Oliver}, doi = {10.1016/j.jmps.2020.104251}, issn = {0022-5096}, journal = {Journal of the Mechanics and Physics of Solids}, pages = 104251, title = {Tangent second-order homogenisation estimates for incompressible hyperelastic composites with fibrous microstructures and anisotropic phases}, url = {https://doi.org/10.1016/j.jmps.2020.104251}, volume = 147, year = 2021 }
2. Walter, J. R., Günther, M., Haeufle, D. F. B., & Schmitt, S. (2021). A geometry- and muscle-based control architecture for synthesising biological movement. Biological Cybernetics. https://doi.org/10.1007/s00422-020-00856-4
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  @article{Walter2021, abstract = {A key problem for biological motor control is to establish a link between an idea of a movement and the generation of a set of muscle-stimulating signals that lead to the movement execution. The number of signals to generate is thereby larger than the body's mechanical degrees of freedom in which the idea of the movement may be easily expressed, as the movement is actually executed in this space. A mathematical formulation that provides a solving link is presented in this paper in the form of a layered, hierarchical control architecture. It is meant to synthesise a wide range of complex three-dimensional muscle-driven movements. The control architecture consists of a `conceptional layer', where the movement is planned, a `structural layer', where the muscles are stimulated, and between both an additional `transformational layer', where the muscle-joint redundancy is resolved. We demonstrate the operativeness by simulating human stance and squatting in a three-dimensional digital human model (DHM). The DHM considers 20 angular DoFs and 36 Hill-type muscle--tendon units (MTUs) and is exposed to gravity, while its feet contact the ground via reversible stick--slip interactions. The control architecture continuously stimulates all MTUs (`structural layer') based on a high-level, torque-based task formulation within its `conceptional layer'. Desired states of joint angles (postural plan) are fed to two mid-level joint controllers in the `transformational layer'. The `transformational layer' communicates with the biophysical structures in the `structural layer' by providing direct MTU stimulation contributions and further input signals for low-level MTU controllers. Thereby, the redundancy of the MTU stimulations with respect to the joint angles is resolved, i.e. a link between plan and execution is established, by exploiting some properties of the biophysical structures modelled. The resulting joint torques generated by the MTUs via their moment arms are fed back to the conceptional layer, closing the high-level control loop. Within our mathematical formulations of the Jacobian matrix-based layer transformations, we identify the crucial information for the redundancy solution to be the muscle moment arms, the stiffness relations of muscle and tendon tissue within the muscle model, and the length--stimulation relation of the muscle activation dynamics. The present control architecture allows the straightforward feeding of conceptional movement task formulations to MTUs. With this approach, the problem of movement planning is eased, as solely the mechanical system has to be considered in the conceptional plan.}, author = {Walter, Johannes R. and G{\"u}nther, Michael and Haeufle, Daniel F. B. and Schmitt, Syn}, day = 15, doi = {10.1007/s00422-020-00856-4}, issn = {1432-0770}, journal = {Biological Cybernetics}, month = {2}, title = {A geometry- and muscle-based control architecture for synthesising biological movement}, url = {https://doi.org/10.1007/s00422-020-00856-4}, year = 2021 }
2020
1. Asgharzadeh, P., Birkhold, A. I., Trivedi, Z., Özdemir, B., Reski, R., & Röhrle, O. (2020). A NanoFE Simulation-based Surrogate Machine Learning Model to Predict Mechanical Functionality of Protein Networks from Live Confocal Imaging. Computational and Structural Biotechnology Journal, 18, 2774–2788. https://doi.org/10.1016/j.csbj.2020.09.024
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  @article{asgharzadeh2020nanofe, author = {Asgharzadeh, Pouyan and Birkhold, Annette I and Trivedi, Zubin and {\"O}zdemir, Bugra and Reski, Ralf and R{\"o}hrle, Oliver}, doi = {https://doi.org/10.1016/j.csbj.2020.09.024}, issn = {2001-0370}, journal = {Computational and Structural Biotechnology Journal}, pages = {2774 - 2788}, publisher = {Elsevier}, title = {A NanoFE Simulation-based Surrogate Machine Learning Model to Predict Mechanical Functionality of Protein Networks from Live Confocal Imaging}, url = {http://www.sciencedirect.com/science/article/pii/S2001037020304086}, volume = 18, year = 2020 }
2. Asgharzadeh, P., Röhrle, O., Willie, B. M., & Birkhold, A. I. (2020). Decoding Rejuvenating Effects of Mechanical Loading on Skeletal Aging using in Vivo microCT Imaging and Deep Learning. Acta Biomaterialia. https://doi.org/10.1016/j.actbio.2020.02.007
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  @article{asgharzadeh2020decoding, author = {Asgharzadeh, Pouyan and R{\"o}hrle, Oliver and Willie, Bettina M and Birkhold, Annette I}, doi = {https://doi.org/10.1016/j.actbio.2020.02.007}, journal = {Acta Biomaterialia}, publisher = {Elsevier}, title = {Decoding Rejuvenating Effects of Mechanical Loading on Skeletal Aging using in Vivo microCT Imaging and Deep Learning}, year = 2020 }
3. Brändle, S., Schmitt, S., & Müller, M. A. (2020). A systems-theoretic analysis of low-level human motor control: application to a single-joint arm model. Journal of Mathematical Biology, 80(4), 1139--1158. https://doi.org/10.1007/s00285-019-01455-z
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  @article{Brändle2020, abstract = {Continuous control using internal models appears to be quite straightforward explaining human motor control. However, it demands both, a high computational effort and a high model preciseness as the whole trajectory needs to be converted. Intermittent control shows great promise for avoiding these drawbacks of continuous control, at least to a certain extent. In this contribution, we study intermittency at the motoneuron level. We ask: how many different, but constant muscle stimulation sets are necessary to generate a stable movement for a specific motor task? Intermittent control, in our perspective, can be assumed only if the number of transitions is relatively small. As application case, a single-joint arm movement is considered. The muscle contraction dynamics is described by a Hill-type muscle model, for the muscle activation dynamics both Hatze's and Zajac's approach are considered. To actuate the lower arm, up to four muscle groups are implemented. A systems-theoretic approach is used to find the smallest number of transitions between constant stimulation sets. A method for a stability analysis of human motion is presented. A Lyapunov function candidate is specified. Thanks to sum-of-squares methods, the presented procedure is generally applicable and computationally feasible. The region-of-attraction of a transition point, and the number of transitions necessary to perform stable arm movements are estimated. The results support the intermittent control theory on this level of motor control, because only very few transitions are necessary.}, author = {Br{\"a}ndle, Stefanie and Schmitt, Syn and M{\"u}ller, Matthias A.}, doi = {10.1007/s00285-019-01455-z}, issn = {1432-1416}, journal = {Journal of Mathematical Biology}, month = {3}, number = 4, pages = {1139--1158}, title = {A systems-theoretic analysis of low-level human motor control: application to a single-joint arm model}, url = {https://doi.org/10.1007/s00285-019-01455-z}, volume = 80, year = 2020 }
4. Emamy, N., Litty, P., Klotz, T., Mehl, M., & Röhrle, O. (2020). POD-DEIM Model Order Reduction for the Monodomain Reaction-Diffusion Sub-Model of the Neuro-Muscular System. IUTAM Symposium on Model Order Reduction of Coupled Systems, Stuttgart, Germany, May 22--25, 2018, 177--190. https://doi.org/10.1007/978-3-030-21013-7_13
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  @article{Nehyat2020, author = {Emamy, Nehzat and Litty, Pascal and Klotz, Thomas and Mehl, Miriam and R{\"o}hrle, Oliver}, doi = {https://doi.org/10.1007/978-3-030-21013-7_13}, journal = {IUTAM Symposium on Model Order Reduction of Coupled Systems, Stuttgart, Germany, May 22--25, 2018}, pages = {177--190}, publisher = {Springer International Publishing}, title = {POD-DEIM Model Order Reduction for the Monodomain Reaction-Diffusion Sub-Model of the Neuro-Muscular System}, year = 2020 }
5. Günther, M., Haeufle, D. F. B., & Schmitt, S. (2020). Corrigendum to “The basic mechanical structure of the skeletal muscle machinery: One model for linking microscopic and macroscopic scales” Journal of Theoretical Biology 456 (2018) 137–167. Journal of Theoretical Biology, 488, 110143. https://doi.org/10.1016/j.jtbi.2019.110143
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  @article{G_nther_2020, author = {Günther, Michael and Haeufle, Daniel F.B. and Schmitt, Syn}, doi = {10.1016/j.jtbi.2019.110143}, journal = {Journal of Theoretical Biology}, month = {3}, pages = 110143, publisher = {Elsevier {BV}}, title = {Corrigendum to {\textquotedblleft}The basic mechanical structure of the skeletal muscle machinery: One model for linking microscopic and macroscopic scales{\textquotedblright} [Journal of Theoretical Biology 456 (2018) 137{\textendash}167]}, url = {https://doi.org/10.1016%2Fj.jtbi.2019.110143}, volume = 488, year = 2020 }
6. Haeufle, D. F. B., Stollenmaier, K., Heinrich, I., Schmitt, S., & Ghazi-Zahedi, K. (2020). Morphological Computation Increases From Lower- to Higher-Level of Biological Motor Control Hierarchy. Frontiers in Robotics and AI, 7. https://doi.org/10.3389/frobt.2020.511265
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  @article{haeufle2020morphological, abstract = {Voluntary movements, like point-to-point or oscillatory human arm movements, are generated by the interaction of several structures. High-level neuronal circuits in the brain are responsible for planning and initiating a movement. Spinal circuits incorporate proprioceptive feedback to compensate for deviations from the desired movement. Muscle biochemistry and contraction dynamics generate movement driving forces and provide an immediate physical response to external forces, like a low-level decentralized controller. A simple central neuronal command like "initiate a movement" then recruits all these biological structures and processes leading to complex behavior, e.g., generate a stable oscillatory movement in resonance with an external spring-mass system. It has been discussed that the spinal feedback circuits, the biochemical processes, and the biomechanical muscle dynamics contribute to the movement generation, and, thus, take over some parts of the movement generation and stabilization which would otherwise have to be performed by the high-level controller. This contribution is termed morphological computation and can be quantified with information entropy-based approaches. However, it is unknown whether morphological computation actually differs between these different hierarchical levels of the control system. To investigate this, we simulated point-to-point and oscillatory human arm movements with a neuro-musculoskeletal model. We then quantify morphological computation on the different hierarchy levels. The results show that morphological computation is highest for the most central (highest) level of the modeled control hierarchy, where the movement initiation and timing are encoded. Furthermore, they show that the lowest neuronal control layer, the muscle stimulation input, exploits the morphological computation of the biochemical and biophysical muscle characteristics to generate smooth dynamic movements. This study provides evidence that the system's design in the mechanical as well as in the neurological structure can take over important contributions to control, which would otherwise need to be performed by the higher control levels.}, author = {Haeufle, Daniel F. B. and Stollenmaier, Katrin and Heinrich, Isabelle and Schmitt, Syn and Ghazi-Zahedi, Keyan}, doi = {10.3389/frobt.2020.511265}, issn = {2296-9144}, journal = {Frontiers in Robotics and AI}, publisher = {Frontiers}, title = {Morphological Computation Increases From Lower- to Higher-Level of Biological Motor Control Hierarchy}, type = {article}, url = {https://www.frontiersin.org/articles/10.3389/frobt.2020.511265/full}, volume = 7, year = 2020 }
7. Haeufle, D. F. B., Siegel, J., Hochstein, S., Gussew, A., Schmitt, S., Siebert, T., Rzanny, R., Reichenbach, J. R., & Stutzig, N. (2020). Energy Expenditure of Dynamic Submaximal Human Plantarflexion Movements: Model Prediction and Validation by in-vivo Magnetic Resonance Spectroscopy. Frontiers in Bioengineering and Biotechnology, 8. https://doi.org/10.3389/fbioe.2020.00622
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  @article{Haeufle_2020, author = {Haeufle, Daniel F. B. and Siegel, Johannes and Hochstein, Stefan and Gussew, Alexander and Schmitt, Syn and Siebert, Tobias and Rzanny, Reinhard and Reichenbach, Jürgen R. and Stutzig, Norman}, doi = {10.3389/fbioe.2020.00622}, journal = {Frontiers in Bioengineering and Biotechnology}, month = {6}, publisher = {Frontiers Media {SA}}, title = {Energy Expenditure of Dynamic Submaximal Human Plantarflexion Movements: Model Prediction and Validation by in-vivo Magnetic Resonance Spectroscopy}, url = {https://doi.org/10.3389%2Ffbioe.2020.00622}, volume = 8, year = 2020 }
8. Haeufle, D. F., Wochner, I., Holzmüller, D., Driess, D., Günther, M., & Schmitt, S. (2020). Muscles reduce neuronal information load: quantification of control effort in biological vs robotic pointing and walking. Frontiers in Robotics and AI, 7, 77. https://doi.org/10.3389/frobt.2020.00077
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  @article{haeufle2020muscles, abstract = {It is hypothesized that the nonlinear muscle characteristic of biomechanical systems simplify control in the sense that the information the nervous system has to process is reduced through off-loading computation to the morphological structure. It has been proposed to quantify the required information with an information-entropy based approach, which evaluates the minimally required information to control a desired movement, i.e., control effort. The key idea is to compare the same movement but generated by different actuators, e.g., muscles and torque actuators, and determine which of the two morphologies requires less information to generate the same movement. In this work, for the first time, we apply this measure to numerical simulations of more complex human movements: point-to-point arm movements and walking. These models consider up to 24 control signals rendering the brute force approach of the previous implementation to search for the minimally required information futile. We therefore propose a novel algorithm based on the pattern search approach specifically designed to solve this constraint optimization problem. We apply this algorithm to numerical models, which include Hill-type muscle-tendon actuation as well as ideal torque sources acting directly on the joints. The controller for the point-to-point movements was obtained by deep reinforcement learning for muscle and torque actuators. Walking was controlled by proprioceptive neural feedback in the muscular system and a PD controller in the torque model. Results show that the neuromuscular models consistently require less information to successfully generate the movement than the torque-driven counterparts. These findings were consistent for all investigated controllers in our experiments, implying that this is a system property, not a controller property. The proposed algorithm to determine the control effort is more efficient than other standard optimization techniques and provided as open source.}, author = {Haeufle, Daniel FB and Wochner, Isabell and Holzm{\"u}ller, David and Driess, Danny and G{\"u}nther, Michael and Schmitt, Syn}, doi = {https://doi.org/10.3389/frobt.2020.00077}, journal = {Frontiers in Robotics and AI}, pages = 77, publisher = {Frontiers}, title = {Muscles reduce neuronal information load: quantification of control effort in biological vs robotic pointing and walking}, url = {https://www.frontiersin.org/articles/10.3389/frobt.2020.00077/full}, volume = 7, year = 2020 }
9. Hessenthaler, A., Balmus, M., Röhrle, O., & Nordsletten, D. (2020). A class of analytic solutions for verification and convergence analysis of linear and nonlinear fluid-structure interaction algorithms. Computer Methods in Applied Mechanics and Engineering, 362, 112841. https://doi.org/10.1016/j.cma.2020.112841
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  @article{hessenthaler2020class, author = {Hessenthaler, Andreas and Balmus, Maximilian and R{\"o}hrle, Oliver and Nordsletten, David}, doi = {https://doi.org/10.1016/j.cma.2020.112841}, journal = {Computer Methods in Applied Mechanics and Engineering}, pages = 112841, publisher = {Elsevier}, title = {A class of analytic solutions for verification and convergence analysis of linear and nonlinear fluid-structure interaction algorithms}, volume = 362, year = 2020 }
10. Hessenthaler, A., Southworth, B. S., Nordsletten, D., Röhrle, O., Falgout, R. D., & Schroder, J. B. (2020). Multilevel convergence analysis of multigrid-reduction-in-time. SIAM Journal on Scientific Computing, 42(2), A771--A796. https://doi.org/10.1137/19M1238812
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  @article{hessenthaler2020multilevel, author = {Hessenthaler, Andreas and Southworth, Ben S and Nordsletten, David and R{\"o}hrle, Oliver and Falgout, Robert D and Schroder, Jacob B}, doi = {https://doi.org/10.1137/19M1238812}, journal = {SIAM Journal on Scientific Computing}, number = 2, pages = {A771--A796}, title = {Multilevel convergence analysis of multigrid-reduction-in-time}, volume = 42, year = 2020 }
11. Klotz, T., Gizzi, L., Yavuz, U., & Röhrle, O. (2020). Modelling the electrical activity of skeletal muscle tissue using a multi-domain approach. Biomechanics and Modelling in Mechanobiology, 19, 335–349. https://doi.org/10.1007/s10237-019-01214-5
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  @article{klotz2020modelling, author = {Klotz, Thomas and Gizzi, Leonardo and Yavuz, Utku and Röhrle, Oliver}, doi = {https://doi.org/10.1007/s10237-019-01214-5}, journal = {Biomechanics and Modelling in Mechanobiology}, pages = {335–349}, title = {Modelling the electrical activity of skeletal muscle tissue using a multi-domain approach}, volume = 19, year = 2020 }
12. Mörl, F., Günther, M., Riede, J. M., Hammer, M., & Schmitt, S. (2020). Loads distributed in vivo among vertebrae, muscles, spinal ligaments, and intervertebral discs in a passively flexed lumbar spine. Biomechanics and Modeling in Mechanobiology, 19(6), 2015--2047. https://doi.org/10.1007/s10237-020-01322-7
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  @article{Mörl2020, abstract = {The load distribution among lumbar spinal structures---still an unanswered question---has been in the focus of this hybrid experimental and simulation study. First, the overall passive resistive torque-angle characteristics of healthy subjects' lumbar spines during flexion--extension cycles in the sagittal plane were determined experimentally by use of a custom-made trunk-bending machine. Second, a forward dynamic computer model of the human body that incorporates a detailed lumbar spine was used to (1) simulate the human--machine interaction in accordance with the experiments and (2) validate the modeled properties of the load-bearing structures. Third, the computer model was used to predict the load distribution in the experimental situation among the implemented lumbar spine structures: muscle--tendon units, ligaments, intervertebral discs, and facet joints. Nine female and 10 male volunteers were investigated. Lumbar kinematics were measured with a marker-based infrared device. The lumbar flexion resistance was measured by the trunk-bending machine through strain gauges on the axes of the machine's torque motors. Any lumbar muscle activity was excluded by simultaneous sEMG monitoring. A mathematical model was used to describe the nonlinear flexion characteristics. The subsequent extension branch of a flexion--extension torque--angle characteristic could be significantly distinguished from its flexion branch by the zero-torque lordosis angle shifted to lower values. A side finding was that the model values of ligament and passive muscle stiffnesses, extracted from well-established literature sources, had to be distinctly reduced in order to approach our measured overall lumbar stiffness values. Even after such parameter adjustment, the computer model still predicts too stiff lumbar spines in most cases in comparison with experimental data. A review of literature data reveals a deficient documentation of anatomical and mechanical parameters of spinal ligaments. For instance, rest lengths of ligaments---a very sensitive parameter for simulations---and cross-sectional areas turned out to be documented at best incompletely. Yet by now, our model well reproduces the literature data of measured pressure values within the lumbar disc at level L4/5. Stretch of the lumbar dorsal (passive) muscle and ligament structures as an inescapable response to flexion can fully explain the pressure values in the lumbar disc. Any further external forces like gravity, or any muscle activities, further increase the compressive load on a vertebral disc. The impact of daily or sportive movements on the loads of the spinal structures other than the disc cannot be predicted ad hoc, because, for example, the load distribution itself crucially determines the structures' current lever arms. In summary, compressive loads on the vertebral discs are not the major determinants, and very likely also not the key indicators, of the load scenario in the lumbar spine. All other structures should be considered at least equally relevant in the future. Likewise, load indicators other than disc compression are advisable to turn attention to. Further, lumbar flexion is a self-contained factor of lumbar load. It may be worthwhile, to take more consciously care of trunk flexion during daily activities, for instance, regarding long-term effects like lasting repetitive flexions or sedentary postures.}, author = {M{\"o}rl, Falk and G{\"u}nther, Michael and Riede, Julia M. and Hammer, Maria and Schmitt, Syn}, day = 01, doi = {10.1007/s10237-020-01322-7}, issn = {1617-7940}, journal = {Biomechanics and Modeling in Mechanobiology}, month = {12}, number = 6, pages = {2015--2047}, title = {Loads distributed in vivo among vertebrae, muscles, spinal ligaments, and intervertebral discs in a passively flexed lumbar spine}, url = {https://doi.org/10.1007/s10237-020-01322-7}, volume = 19, year = 2020 }
13. Rockenfeller, R., Günther, M., Stutzig, N., Haeufle, D. F. B., Siebert, T., Schmitt, S., Leichsenring, K., Böl, M., & Götz, T. (2020). Exhaustion of Skeletal Muscle Fibers Within Seconds: Incorporating Phosphate Kinetics Into a Hill-Type Model. Frontiers in Physiology, 11. https://doi.org/10.3389/fphys.2020.00306
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  @article{Rockenfeller_2020, author = {Rockenfeller, Robert and Günther, Michael and Stutzig, Norman and Haeufle, Daniel F. B. and Siebert, Tobias and Schmitt, Syn and Leichsenring, Kay and Böl, Markus and Götz, Thomas}, doi = {10.3389/fphys.2020.00306}, journal = {Frontiers in Physiology}, month = {5}, publisher = {Frontiers Media {SA}}, title = {Exhaustion of Skeletal Muscle Fibers Within Seconds: Incorporating Phosphate Kinetics Into a Hill-Type Model}, url = {https://doi.org/10.3389%2Ffphys.2020.00306}, volume = 11, year = 2020 }
14. Saini, H., Ackland, D. C., Gong, L., Cheng, L. K., & Röhrle, O. (2020). Occlusal load modelling significantly impacts the predicted tooth stress response during biting: a simulation study. Computer Methods in Biomechanics and Biomedical Engineering, 1--10. https://doi.org/10.1080/10255842.2020.1711886
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  @article{saini2020occlusal, author = {Saini, Harnoor and Ackland, David C and Gong, Lulu and Cheng, Leo K and R{\"o}hrle, Oliver}, doi = {https://doi.org/10.1080/10255842.2020.1711886}, journal = {Computer Methods in Biomechanics and Biomedical Engineering}, pages = {1--10}, publisher = {Taylor \& Francis}, title = {Occlusal load modelling significantly impacts the predicted tooth stress response during biting: a simulation study}, year = 2020 }
15. Walter, J. R., Saini, H., Maier, B., Mostashiri, N., Aguayo, J. L., Zarshenas, H., Hinze, C., Shuva, S., Köhler, J., Sahrmann, A. S., Chang, C., Csiszar, A., Galliani, S., Cheng, L. K., & Röhrle, O. (2020). Comparative Study of a Biomechanical Model-based and Black-box Approach for Subject-Specific Movement Prediction. 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 4775--4778. https://doi.org/10.1109/EMBC44109.2020.9176600
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  @inproceedings{walter2020comparative, author = {Walter, Johannes R. and Saini, Harnoor and Maier, Benjamin and Mostashiri, Naser and Aguayo, Jaime L. and Zarshenas, Homayoon and Hinze, Christoph and Shuva, Shahnewaz and Köhler, Johannes and Sahrmann, Annika S. and Chang, Che-ming and Csiszar, Akos and Galliani, Simona and Cheng, Leo K. and Röhrle, Oliver}, booktitle = {2020 42nd Annual International Conference of the IEEE Engineering in Medicine \& Biology Society (EMBC)}, doi = {https://doi.org/10.1109/EMBC44109.2020.9176600}, organization = {IEEE}, pages = {4775--4778}, title = {Comparative Study of a Biomechanical Model-based and Black-box Approach for Subject-Specific Movement Prediction}, type = {Publication}, year = 2020 }
16. Wochner, I., Driess, D., Zimmermann, H., Haeufle, D. F., Toussaint, M., & Schmitt, S. (2020). Optimality principles in human point-to-manifold reaching accounting for muscle dynamics. Frontiers in Computational Neuroscience, 14, 38. https://doi.org/10.3389/fncom.2020.00038
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  @article{wochner2020optimality, abstract = {Human arm movements are highly stereotypical under a large variety of experimental conditions. This is striking due to the high redundancy of the human musculoskeletal system, which in principle allows many possible trajectories toward a goal. Many researchers hypothesize that through evolution, learning, and adaption, the human system has developed optimal control strategies to select between these possibilities. Various optimality principles were proposed in the literature that reproduce human-like trajectories in certain conditions. However, these studies often focus on a single cost function and use simple torque-driven models of motion generation, which are not consistent with human muscle-actuated motion. The underlying structure of our human system, with the use of muscle dynamics in interaction with the control principles, might have a significant influence on what optimality principles best model human motion. To investigate this hypothesis, we consider a point-to-manifold reaching task that leaves the target underdetermined. Given hypothesized motion objectives, the control input is generated using Bayesian optimization, which is a machine learning based method that trades-off exploitation and exploration. Using numerical simulations with Hill-type muscles, we show that a combination of optimality principles best predicts human point-to-manifold reaching when accounting for the muscle dynamics.}, author = {Wochner, Isabell and Driess, Danny and Zimmermann, Heiko and Haeufle, Daniel FB and Toussaint, Marc and Schmitt, Syn}, doi = {https://doi.org/10.3389/fncom.2020.00038}, journal = {Frontiers in Computational Neuroscience}, pages = 38, publisher = {Frontiers}, title = {Optimality principles in human point-to-manifold reaching accounting for muscle dynamics}, url = {https://www.frontiersin.org/articles/10.3389/fncom.2020.00038/full}, volume = 14, year = 2020 }
2019
1. Bleiler, C., Ponte Castañeda, P., & Röhrle, O. (2019). A microstructurally-based, multi-scale, continuum-mechanical model for the passive behaviour of skeletal muscle tissue. Journal of the Mechanical Behavior of Biomedical Materials, 97, 171--186. https://doi.org/10.1016/j.jmbbm.2019.05.012
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  @article{bleiler2019microstructurally, author = {Bleiler, Christian and Ponte Casta{\~n}eda, Pedro and R{\"o}hrle, Oliver}, doi = {https://doi.org/10.1016/j.jmbbm.2019.05.012}, journal = {Journal of the Mechanical Behavior of Biomedical Materials}, pages = {171--186}, publisher = {Elsevier}, title = {A microstructurally-based, multi-scale, continuum-mechanical model for the passive behaviour of skeletal muscle tissue}, volume = 97, year = 2019 }
2. Driess, D., Schmitt, S., & Toussaint, M. (2019). Active Inverse Model Learning with Error and Reachable Set Estimates. Proc. of the IEEE Int. Conf. on Intelligent Robotsand Systems (IROS). https://doi.org/10.1109/IROS40897.2019.8967858
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  @inproceedings{19-driess-IROS, author = {Driess, Danny and Schmitt, Syn and Toussaint, Marc}, booktitle = {Proc{.} of the IEEE Int{.} Conf{.} on Intelligent Robotsand Systems (IROS)}, doi = {10.1109/IROS40897.2019.8967858}, title = {Active Inverse Model Learning with Error and Reachable Set Estimates}, year = 2019, youtube = {3ks0sMa3BgM} }
3. Gizzi, L., Röhrle, O., Petzke, F., & Falla, D. (2019). People with low back pain show reduced movement complexity during their most active daily tasks. European Journal of Pain, 23(2), 410--418. https://doi.org/10.1002/ejp.1318
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  @article{gizzi2019people, author = {Gizzi, Leonardo and R{\"o}hrle, Oliver and Petzke, Frank and Falla, Deborah}, doi = {https://doi.org/10.1002/ejp.1318}, journal = {European Journal of Pain}, number = 2, pages = {410--418}, publisher = {Wiley Online Library}, title = {People with low back pain show reduced movement complexity during their most active daily tasks}, volume = 23, year = 2019 }
4. Hammer, M., Günther, M., Haeufle, D. F. B., & Schmitt, S. (2019). Tailoring anatomical muscle paths: a sheath-like solution for muscle routing in musculoskeletal computer models. Mathematical Biosciences, 311, 68–81. https://doi.org/10.1016/j.mbs.2019.02.004
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  @article{Hammer2019a, abstract = {Muscle wrapping geometry has a major impact on the muscle force as well as the torque onto the joint exerted by this muscle since these torques highly depend on the muscle’s line of action or, in other words, the muscle moment arm. Most common redirection methods focus on two-dimensional motions and optimise path geometry for only one isolated movement, either flexion, abduction or rotation, instead of covering all degrees of freedom (DOFs). Others can only imitate anatomical paths in a small working range or for single joint movements. For biomechanical simulations of sweeping movements like running or throwing, however, a correct representation of muscle paths for a large range of joint configurations is mandatory. We introduce a new computational algorithm for modelling the muscle path in three-dimensional biomechanical simulations, based on a model description of muscles as massless, visco-elastic strands and the assumption that the muscle acts along a continuous path consisting of piecewise straight lines. In the presented approach, anatomical constraints including bones, tendon sheaths and other surrounding tissue are represented by areas the muscle has to pass. We model these redirection constraints as ellipses, allowing the muscle path to move within these areas and along their frictionless, inner edges. We show that – by only adjusting ellipse parameters – we are able to achieve reasonable moment arms for all (DOFs) and for a large range of joint configurations of uniarticular muscles as well as muscles spanning more than one joint – even for complex geometries.}, author = {Hammer, M. and Günther, M. and Haeufle, D.F.B. and Schmitt, S.}, doi = {https://doi.org/10.1016/j.mbs.2019.02.004}, issn = {0025-5564}, journal = {Mathematical Biosciences}, pages = {68 - 81}, title = {Tailoring anatomical muscle paths: a sheath-like solution for muscle routing in musculoskeletal computer models}, url = {http://www.sciencedirect.com/science/article/pii/S0025556418302542}, volume = 311, year = 2019 }
5. Röhrle, O., Yavuz, U. S., Klotz, T., Negro, F., & Heidlauf, T. (2019). Multiscale modeling of the neuromuscular system: Coupling neurophysiology and skeletal muscle mechanics. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, e1457.
  - BibTeX
  BibTeX
  @article{rohrlemultiscale, author = {R{\"o}hrle, Oliver and Yavuz, Utku {\c{S}} and Klotz, Thomas and Negro, Francesco and Heidlauf, Thomas}, journal = {Wiley Interdisciplinary Reviews: Systems Biology and Medicine}, pages = {e1457}, publisher = {John Wiley \& Sons, Inc. Hoboken, USA}, title = {Multiscale modeling of the neuromuscular system: Coupling neurophysiology and skeletal muscle mechanics}, year = 2019 }
6. Schmid, L., Klotz, T., Siebert, T., & Röhrle, O. (2019). Characterization of electromechanical delay based on a biophysical multi-scale skeletal muscle model. Frontiers in Physiology, 10, 1270. https://doi.org/10.3389/fphys.2019.01270
  - BibTeX
  BibTeX
  @article{schmid2019characterization, author = {Schmid, Laura and Klotz, Thomas and Siebert, Tobias and Röhrle, Oliver}, doi = {10.3389/fphys.2019.01270}, issn = {1664-042X}, journal = {Frontiers in Physiology}, pages = 1270, title = {Characterization of electromechanical delay based on a biophysical multi-scale skeletal muscle model}, url = {https://www.frontiersin.org/article/10.3389/fphys.2019.01270}, volume = 10, year = 2019 }
7. Schmitt, S., Günther, M., & Häufle, D. F. (2019). The dynamics of the skeletal muscle: A systems biophysics perspective on muscle modeling with the focus on Hill-type muscle models. GAMM-Mitteilungen, e201900013.
  - BibTeX
  BibTeX
  @article{schmitt2019dynamics, __markedentry = {[syn:]}, author = {Schmitt, Syn and G{\"u}nther, Michael and H{\"a}ufle, Daniel FB}, journal = {GAMM-Mitteilungen}, pages = {e201900013}, publisher = {Wiley Online Library}, title = {The dynamics of the skeletal muscle: A systems biophysics perspective on muscle modeling with the focus on Hill-type muscle models}, year = 2019 }
8. Tomalka, A., Röhrle, O., Han, J.-C., Pham, T., Taberner, A. J., & Siebert, T. (2019). Extensive eccentric contractions in intact cardiac trabeculae: revealing compelling differences in contractile behaviour compared to skeletal muscles. Proceedings of the Royal Society B, 286(1903), 20190719.
  - BibTeX
  BibTeX
  @article{tomalka2019extensive, author = {Tomalka, Andr{\'e} and R{\"o}hrle, Oliver and Han, June-Chiew and Pham, Toan and Taberner, Andrew J and Siebert, Tobias}, journal = {Proceedings of the Royal Society B}, number = 1903, pages = 20190719, publisher = {The Royal Society}, title = {Extensive eccentric contractions in intact cardiac trabeculae: revealing compelling differences in contractile behaviour compared to skeletal muscles}, volume = 286, year = 2019 }
2018
1. Asgharzadeh, P., Özdemir, B., Reski, R., Röhrle, O., & Birkhold, A. I. (2018). Computational 3D imaging to quantify structural components and assembly of protein networks. Acta Biomaterialia, 69, 206--217.
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  BibTeX
  @article{asgharzadeh2018computational, author = {Asgharzadeh, Pouyan and {\"O}zdemir, Bugra and Reski, Ralf and R{\"o}hrle, Oliver and Birkhold, Annette I}, journal = {Acta biomaterialia}, pages = {206--217}, publisher = {Elsevier}, title = {Computational 3D imaging to quantify structural components and assembly of protein networks}, volume = 69, year = 2018 }
2. Bradley, C. P., Emamy, N., Ertl, T., Göddeke, D., Hessenthaler, A., Klotz, T., Krämer, A., Krone, M., Maier, B., Mehl, M., Rau, T., & Röhrle, O. (2018). Enabling Detailed, Biophysics-Based Skeletal Muscle Models on HPC Systems. Frontiers in Physiology, 9. https://doi.org/10.3389/fphys.2018.00816
  - BibTeX
  BibTeX
  @article{bradley2018enabling, affiliation = {Rohrle, O (Reprint Author), Univ Stuttgart, Stuttgart Ctr Simulat Sci, Stuttgart, Germany. Rohrle, O (Reprint Author), Univ Stuttgart, Inst Appl Mech CE, SimTech Res Grp Continuum Biomech \& Mechanobiol, Stuttgart, Germany. Bradley, Chris P., Univ Auckland, Auckland Bioengn Inst, Auckland, New Zealand. Emamy, Nehzat; Maier, Benjamin; Mehl, Miriam, Univ Stuttgart, Inst Parallel \& Distributed Syst, Stuttgart, Germany. Emamy, Nehzat; Ertl, Thomas; Goeddeke, Dominik; Hessenthaler, Andreas; Klotz, Thomas; Kraemer, Aaron; Krone, Michael; Maier, Benjamin; Mehl, Miriam; Rau, Tobias; Roehrle, Oliver, Univ Stuttgart, Stuttgart Ctr Simulat Sci, Stuttgart, Germany. Ertl, Thomas; Krone, Michael; Rau, Tobias, Univ Stuttgart, Visualizat Res Ctr, Stuttgart, Germany. Goeddeke, Dominik; Kraemer, Aaron, Univ Stuttgart, Inst Appl Anal \& Numer Simulat, Stuttgart, Germany. Hessenthaler, Andreas; Klotz, Thomas; Roehrle, Oliver, Univ Stuttgart, Inst Appl Mech CE, SimTech Res Grp Continuum Biomech \& Mechanobiol, Stuttgart, Germany.}, article-number = {816}, author = {Bradley, Chris P. and Emamy, Nehzat and Ertl, Thomas and Göddeke, Dominik and Hessenthaler, Andreas and Klotz, Thomas and Krämer, Aaron and Krone, Michael and Maier, Benjamin and Mehl, Miriam and Rau, Tobias and Röhrle, Oliver}, da = {2019-03-07}, doi = {10.3389/fphys.2018.00816}, issn = {1664-042X}, journal = {Frontiers in Physiology}, language = {English}, month = {JUL 12}, oa = {DOAJ Gold}, orcid-numbers = {Ertl, Thomas/0000-0003-4019-2505 Krone, Michael/0000-0002-1445-7568 Hessenthaler, Andreas/0000-0003-2681-5315}, publisher = {FRONTIERS MEDIA SA}, research-areas = {Physiology}, title = {Enabling Detailed, Biophysics-Based Skeletal Muscle Models on HPC Systems}, type = {Article}, unique-id = {ISI:000438394100001}, volume = 9, year = 2018 }
3. Driess, D., Zimmermann, H., Wolfen, S., Suissa, D., Haeufle, D., Hennes, D., Toussaint, M., & Schmitt, S. (2018). Learning to Control Redundant Musculoskeletal Systems with Neural Networks and SQP: Exploiting Muscle Properties. Proc. of the International Conference on Robotics and Automation.
  - BibTeX
  BibTeX
  @inproceedings{Driess2018a, author = {Driess, Danny and Zimmermann, Heiko and Wolfen, Simon and Suissa, Dan and Haeufle, Daniel and Hennes, Daniel and Toussaint, Marc and Schmitt, Syn}, booktitle = {Proc. of the International Conference on Robotics and Automation}, title = {Learning to Control Redundant Musculoskeletal Systems with Neural Networks and {SQP}: Exploiting Muscle Properties}, year = 2018, youtube = {ODFvqBWOtec} }
4. Eggs, B., Birkhold, A. I., Röhrle, O., & Betz, O. (2018). Structure and function of the musculoskeletal ovipositor system of an ichneumonid wasp. BMC Zoology, 3(1), 12.
  - BibTeX
  BibTeX
  @article{eggs2018structure, author = {Eggs, Benjamin and Birkhold, Annette I and R{\"o}hrle, Oliver and Betz, Oliver}, journal = {BMC Zoology}, number = 1, pages = 12, publisher = {BioMed Central}, title = {Structure and function of the musculoskeletal ovipositor system of an ichneumonid wasp}, volume = 3, year = 2018 }
5. Günther, M., Häufle, D., & Schmitt, S. (2018). The basic mechanical structure of the skeletal muscle machinery: One model for linking microscopic and macroscopic scales.
  - BibTeX
  BibTeX
  @article{gunther2018basic, author = {Günther, Michael and Häufle, Daniel and Schmitt, Syn}, title = {The basic mechanical structure of the skeletal muscle machinery: One model for linking microscopic and macroscopic scales}, year = 2018 }
6. Günther, M., Haeufle, D. F., & Schmitt, S. (2018). The basic mechanical structure of the skeletal muscle machinery: One model for linking microscopic and macroscopic scales. Journal of Theoretical Biology, 456, 137--167.
  - BibTeX
  BibTeX
  @article{gunther2018basic, __markedentry = {[syn:]}, author = {G{\"u}nther, Michael and Haeufle, Daniel FB and Schmitt, Syn}, journal = {Journal of Theoretical Biology}, pages = {137--167}, publisher = {Elsevier}, title = {The basic mechanical structure of the skeletal muscle machinery: One model for linking microscopic and macroscopic scales}, volume = 456, year = 2018 }
7. Haeufle, D. F., Schmortte, B., Geyer, H., Müller, R., & Schmitt, S. (2018). The benefit of combining neuronal feedback and feed-forward control for robustness in step down perturbations of simulated human walking depends on the muscle function. Frontiers in Computational Neuroscience, 12, 80.
  - BibTeX
  BibTeX
  @article{haeufle2018benefit, author = {Haeufle, Daniel FB and Schmortte, Birgit and Geyer, Hartmut and M{\"u}ller, Roy and Schmitt, Syn}, journal = {Frontiers in Computational Neuroscience}, pages = 80, publisher = {Frontiers}, title = {The benefit of combining neuronal feedback and feed-forward control for robustness in step down perturbations of simulated human walking depends on the muscle function}, volume = 12, year = 2018 }
8. Hessenthaler, A., Nordsletten, D., Röhrle, O., Schroder, J. B., & Falgout, R. D. (2018). Convergence of the multigrid reduction in time algorithm for the linear elasticity equations. Numerical Linear Algebra with Applications, 25(3), e2155.
  - BibTeX
  BibTeX
  @article{hessenthaler2018convergence, author = {Hessenthaler, Andreas and Nordsletten, David and R{\"o}hrle, Oliver and Schroder, Jacob B and Falgout, Robert D}, journal = {Numerical Linear Algebra with Applications}, number = 3, pages = {e2155}, title = {Convergence of the multigrid reduction in time algorithm for the linear elasticity equations}, volume = 25, year = 2018 }
9. Hoekstra, A. G., van de Vosse, F., & Röhrle, O. (2018). The virtual physiological human conference 2016. Journal of Computational Science, 24, 65--67.
  - BibTeX
  BibTeX
  @article{hoekstra2018virtual, author = {Hoekstra, Alfons G and van de Vosse, Frans and R{\"o}hrle, Oliver}, journal = {Journal of computational science}, pages = {65--67}, title = {The virtual physiological human conference 2016}, volume = 24, year = 2018 }
10. Ramasamy, E., Avci, O., Dorow, B., Chong, S.-Y., Gizzi, L., Steidle, G., Schick, F., & Röhrle, O. (2018). An efficient modelling-simulation-analysis workflow to investigate stump-socket interaction using patient-specific, three-dimensional, continuum-mechanical, finite element residual limb models. Frontiers in Bioengineering and Biotechnology, 6.
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  BibTeX
  @article{ramasamy2018efficient, author = {Ramasamy, Ellankavi and Avci, Okan and Dorow, Beate and Chong, Sook-Yee and Gizzi, Leonardo and Steidle, Guenter and Schick, Fritz and R{\"o}hrle, Oliver}, journal = {Frontiers in bioengineering and biotechnology}, publisher = {Frontiers Media SA}, title = {An efficient modelling-simulation-analysis workflow to investigate stump-socket interaction using patient-specific, three-dimensional, continuum-mechanical, finite element residual limb models}, volume = 6, year = 2018 }
11. Roehrle, O., Saini, H., & Ackland, D. C. (2018). Occlusal loading during biting from an experimental and simulation point of view. Dental Materials, 34(1), 58--68.
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  BibTeX
  @article{roehrle2018occlusal, author = {Roehrle, Oliver and Saini, Harnoor and Ackland, David C}, journal = {Dental Materials}, number = 1, pages = {58--68}, publisher = {Elsevier}, title = {Occlusal loading during biting from an experimental and simulation point of view}, volume = 34, year = 2018 }
12. Röhrle, O., Saini, H., Lee, P. V., & Ackland, D. C. (2018). A novel computational method to determine subject-specific bite force and occlusal loading during mastication. Computer Methods in Biomechanics and Biomedical Engineering, 21(6), 453--460.
  - BibTeX
  BibTeX
  @article{rohrle2018novel, author = {R{\"o}hrle, Oliver and Saini, Harnoor and Lee, Peter VS and Ackland, David C}, journal = {Computer methods in biomechanics and biomedical engineering}, number = 6, pages = {453--460}, publisher = {Taylor \& Francis}, title = {A novel computational method to determine subject-specific bite force and occlusal loading during mastication}, volume = 21, year = 2018 }
13. Schneider, M., Buschbaum, J., Joeris, A., Röhrle, O., Dwyer, J., Hunter, J. B., Reynolds, R. A., Slongo, T. F., Gueorguiev, B., & Varga, P. (2018). Biomechanical investigation of two long bone growth modulation techniques by finite element simulations. Journal of Orthopaedic Research®, 36(5), 1398--1405.
  - BibTeX
  BibTeX
  @article{schneider2018biomechanical, author = {Schneider, Manuel and Buschbaum, Jan and Joeris, Alexander and R{\"o}hrle, Oliver and Dwyer, Jonathan and Hunter, James B and Reynolds, Richard AK and Slongo, Theodor F and Gueorguiev, Boyko and Varga, Peter}, journal = {Journal of Orthopaedic Research{\textregistered}}, number = 5, pages = {1398--1405}, title = {Biomechanical investigation of two long bone growth modulation techniques by finite element simulations}, volume = 36, year = 2018 }
14. Suissa, D., Günther, M., Shapiro, A., Melzer, I., & Schmitt, S. (2018). On Laterally Perturbed Human Stance: Experiment, Model, and Control. Applied Bionics and Biomechanics, 2018, 20. https://doi.org/10.1155/2018/4767624
  - BibTeX
  BibTeX
  @article{Suissa2018a, author = {Suissa, Dan and G{\"u}nther, Michael and Shapiro, Amir and Melzer, Itshak and Schmitt, Syn}, doi = {10.1155/2018/4767624}, journal = {Applied Bionics and Biomechanics}, pages = 20, title = {On Laterally Perturbed Human Stance: Experiment, Model, and Control}, url = {https://doi.org/10.1155/2018/4767624}, volume = 2018, year = 2018 }
15. Valentin, J., Sprenger, M., Pflüger, D., & Röhrle, O. (2018). Gradient-based optimization with B-splines on sparse grids for solving forward-dynamics simulations of three-dimensional, continuum-mechanical musculoskeletal system models. International Journal for Numerical Methods in Biomedical Engineering, 34(5), e2965.
  - BibTeX
  BibTeX
  @article{valentin2018gradient, author = {Valentin, J and Sprenger, M and Pfl{\"u}ger, D and R{\"o}hrle, O}, journal = {International journal for numerical methods in biomedical engineering}, number = 5, pages = {e2965}, title = {Gradient-based optimization with B-splines on sparse grids for solving forward-dynamics simulations of three-dimensional, continuum-mechanical musculoskeletal system models}, volume = 34, year = 2018 }
16. Wolfen, S., Walter, J., Günther, M., Haeufle, D. F. B., & Schmitt, S. (2018). Bioinspired pneumatic muscle spring units mimicking the human motion apparatus: benefits for passive motion range and joint stiffness variation in antagonistic setups. 2018 25th International Conference on Mechatronics and Machine Vision in Practice (M2VIP), 1--6. https://doi.org/10.1109/M2VIP.2018.8600913
  - BibTeX
  BibTeX
  @inproceedings{Wolfen2018a, author = {Wolfen, S. and Walter, J. and G{\"u}nther, M. and Haeufle, D. F. B. and Schmitt, S.}, booktitle = {25th International Conference on Mechatronics and Machine Vision in Practice (M2VIP)}, date-added = {2019-02-14 16:52:44 +0100}, date-modified = {2019-02-14 16:52:57 +0100}, doi = {10.1109/M2VIP.2018.8600913}, journal = {2018 25th International Conference on Mechatronics and Machine Vision in Practice (M2VIP)}, journal1 = {2018 25th International Conference on Mechatronics and Machine Vision in Practice (M2VIP)}, pages = {1--6}, title = {Bioinspired pneumatic muscle spring units mimicking the human motion apparatus: benefits for passive motion range and joint stiffness variation in antagonistic setups}, ty = {CONF}, year = 2018 }
17. Özdemir, B., Asgharzadeh, P., Birkhold, A. I., Mueller, S. J., Röhrle, O., & Reski, R. (2018). Cytological analysis and structural quantification of FtsZ1-2 and FtsZ2-1 network characteristics in Physcomitrella patens. Scientific Reports, 8(1), 11165.
  - BibTeX
  BibTeX
  @article{ozdemir2018cytological, author = {{\"O}zdemir, Bugra and Asgharzadeh, Pouyan and Birkhold, Annette I and Mueller, Stefanie J and R{\"o}hrle, Oliver and Reski, Ralf}, journal = {Scientific reports}, number = 1, pages = 11165, publisher = {Nature Publishing Group}, title = {Cytological analysis and structural quantification of FtsZ1-2 and FtsZ2-1 network characteristics in Physcomitrella patens}, volume = 8, year = 2018 }
2017
1. Bayer, A., Schmitt, S., Günther, M., & Haeufle, D. (2017). The influence of biophysical muscle properties on simulating fast human arm movements. Computer Methods in Biomechanics and Biomedical Engineering, 20(8), 803--821.
  - BibTeX
  BibTeX
  @article{bayer2017influence, author = {Bayer, A and Schmitt, S and G{\"u}nther, M and Haeufle, DFB}, journal = {{Computer Methods in Biomechanics and Biomedical Engineering}}, number = 8, pages = {803--821}, publisher = {Taylor \& Francis}, title = {The influence of biophysical muscle properties on simulating fast human arm movements}, volume = 20, year = 2017 }
2. Brown, N., Bubeck, D., Haeufle, D. F. B., Weickenmeier, J., Kuhl, E., Alt, W., & Schmitt, S. (2017). Weekly Time Course of Neuro-Muscular Adaptation to Intensive Strength Training. Frontiers in Physiology, 8, 329. https://doi.org/10.3389/fphys.2017.00329
  - BibTeX
  BibTeX
  @article{Brown2017a, author = {Brown, Niklas and Bubeck, Dieter and Haeufle, Daniel F. B. and Weickenmeier, Johannes and Kuhl, Ellen and Alt, Wilfried and Schmitt, Syn}, doi = {10.3389/fphys.2017.00329}, issn = {1664-042X}, journal = {Frontiers in Physiology}, pages = 329, title = {Weekly Time Course of Neuro-Muscular Adaptation to Intensive Strength Training}, url = {http://journal.frontiersin.org/article/10.3389/fphys.2017.00329}, volume = 8, year = 2017 }
3. Christensen, K. B., Günther, M., Schmitt, S., & Siebert, T. (2017). Strain in shock-loaded skeletal muscle and the time scale of muscular wobbling mass dynamics. Scientific Reports, 7(1), 13266. https://doi.org/10.1038/s41598-017-13630-7
  - BibTeX
  BibTeX
  @article{Christensen2017a, abstract = {In terrestrial locomotion, muscles undergo damped oscillations in response to limb impacts with the ground. Muscles are also actuators that generate mechanical power to allow locomotion. The corresponding elementary contractile process is the work stroke of an actin-myosin cross-bridge, which may be forcibly detached by superposed oscillations. By experimentally emulating rat leg impacts, we found that full activity and non-fatigue must meet to possibly prevent forcible cross-bridge detachment. Because submaximal muscle force represents the ordinary locomotor condition, our results show that forcible, eccentric cross-bridge detachment is a common, physiological process even during isometric muscle contractions. We also calculated the stiffnesses of the whole muscle-tendon complex and the fibre material separately, as well as Young’s modulus of the latter: 1.8 MPa and 0.75 MPa for fresh, fully active and passive fibres, respectively. Our inferred Young’s modulus of the tendon-aponeurosis complex suggests that stiffness in series to the fibre material is determined by the elastic properties of the aponeurosis region, rather than the tendon material. Knowing these stiffnesses and the muscle mass, the complex’ eigenfrequency for responses to impacts can be quantified, as well as the size-dependency of this time scale of muscular wobbling mass dynamics.}, author = {Christensen, Kasper B. and Günther, Michael and Schmitt, Syn and Siebert, Tobias}, issn = {2045-2322}, journal = {Scientific Reports}, month = oct, number = 1, pages = 13266, refid = {Christensen2017a}, title = {Strain in shock-loaded skeletal muscle and the time scale of muscular wobbling mass dynamics}, url = {https://doi.org/10.1038/s41598-017-13630-7}, volume = 7, year = 2017 }
4. Heidlauf, T., Klotz, T., Rode, C., Siebert, T., & Röhrle, O. (2017). A continuum-mechanical skeletal muscle model including actin-titin interaction predicts stable contractions on the descending limb of the force-length relation. PLoS Computational Biology, 13(10), e1005773.
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  BibTeX
  @article{heidlauf2017continuum, author = {Heidlauf, Thomas and Klotz, Thomas and Rode, Christian and Siebert, Tobias and R{\"o}hrle, Oliver}, journal = {PLoS computational biology}, number = 10, pages = {e1005773}, publisher = {Public Library of Science}, title = {A continuum-mechanical skeletal muscle model including actin-titin interaction predicts stable contractions on the descending limb of the force-length relation}, volume = 13, year = 2017 }
5. Hessenthaler, A., Gaddum, N., Holub, O., Sinkus, R., Röhrle, O., & Nordsletten, D. (2017). Experiment for validation of fluid-structure interaction models and algorithms. International Journal for Numerical Methods in Biomedical Engineering, 33(9), e2848.
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  BibTeX
  @article{hessenthaler2017experiment, author = {Hessenthaler, A and Gaddum, NR and Holub, O and Sinkus, R and R{\"o}hrle, O and Nordsletten, D}, journal = {International journal for numerical methods in biomedical engineering}, number = 9, pages = {e2848}, title = {Experiment for validation of fluid-structure interaction models and algorithms}, volume = 33, year = 2017 }
6. Hessenthaler, A., Röhrle, O., & Nordsletten, D. (2017). Validation of a non-conforming monolithic fluid-structure interaction method using phase-contrast MRI. International Journal for Numerical Methods in Biomedical Engineering, 33(8), e2845.
  - BibTeX
  BibTeX
  @article{hessenthaler2017validation, author = {Hessenthaler, Andreas and R{\"o}hrle, Oliver and Nordsletten, David}, journal = {International journal for numerical methods in biomedical engineering}, number = 8, pages = {e2845}, title = {Validation of a non-conforming monolithic fluid-structure interaction method using phase-contrast MRI}, volume = 33, year = 2017 }
7. Kleinbach, C., Martynenko, O., Promies, J., Haeufle, D. F., Fehr, J., & Schmitt, S. (2017). Implementation and validation of the extended Hill-type muscle model with robust routing capabilities in LS-DYNA for active human body models. Biomedical Engineering Online, 16(1), 109.
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  BibTeX
  @article{kleinbach2017implementation, __markedentry = {[syn:]}, author = {Kleinbach, Christian and Martynenko, Oleksandr and Promies, Janik and Haeufle, Daniel FB and Fehr, J{\"o}rg and Schmitt, Syn}, journal = {Biomedical Engineering Online}, number = 1, pages = 109, publisher = {BioMed Central}, title = {Implementation and validation of the extended Hill-type muscle model with robust routing capabilities in LS-DYNA for active human body models}, volume = 16, year = 2017 }
8. Krohn, B., Sathar, S., Röhrle, O., Vanderwinden, J.-M., O, & Cheng, L. K. (2017). A framework for simulating gastric electrical propagation in confocal microscopy derived geometries. 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 4215--4218.
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  BibTeX
  @inproceedings{krohn2017framework, author = {Krohn, Berit and Sathar, Shameer and R{\"o}hrle, Oliver and Vanderwinden, Jean-Marie and O'Grady, Gregory and Cheng, Leo K}, booktitle = {2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)}, organization = {IEEE}, pages = {4215--4218}, title = {A framework for simulating gastric electrical propagation in confocal microscopy derived geometries}, year = 2017 }
9. Lindemann, U., Schwenk, M., Schmitt, S., Weyrich, M., Schlicht, W., & Becker, C. (2017). Effect of uphill and downhill walking on walking performance in geriatric patients using a wheeled walker. Zeitschrift Für Gerontologie Und Geriatrie, 50(6), 483--487.
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  BibTeX
  @article{lindemann2017effect, __markedentry = {[syn:6]}, author = {Lindemann, Ulrich and Schwenk, Michael and Schmitt, Syn and Weyrich, Michael and Schlicht, Wolfgang and Becker, Clemens}, journal = {Zeitschrift f{\"u}r Gerontologie und Geriatrie}, number = 6, pages = {483--487}, publisher = {Springer}, title = {Effect of uphill and downhill walking on walking performance in geriatric patients using a wheeled walker}, volume = 50, year = 2017 }
10. Mordhorst, M., Strecker, T., Wirtz, D., Heidlauf, T., & Röhrle, O. (2017). POD-DEIM reduction of computational EMG models. Journal of Computational Science, 19, 86--96.
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  BibTeX
  @article{mordhorst2017pod, author = {Mordhorst, M and Strecker, Timm and Wirtz, D and Heidlauf, Thomas and R{\"o}hrle, Oliver}, journal = {Journal of Computational Science}, pages = {86--96}, publisher = {Elsevier}, title = {POD-DEIM reduction of computational EMG models}, volume = 19, year = 2017 }
11. Rockenfeller, R., Günther, M., Schmitt, S., & Götz, T. (2017). Corrigendum to “Comparative Sensitivity Analysis of Muscle Activation Dynamics.” Computational and Mathematical Methods in Medicine, 2017, 2. https://doi.org/10.1155/2017/6752731
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  BibTeX
  @article{Rockenfeller2017a, author = {Rockenfeller, Robert and G{\"u}nther, Michael and Schmitt, Syn and G{\"o}tz, Thomas}, doi = {10.1155/2017/6752731}, journal = {Computational and Mathematical Methods in Medicine}, pages = 2, title = {Corrigendum to 'Comparative Sensitivity Analysis of Muscle Activation Dynamics'}, url = {https://doi.org/10.1155/2017/6752731}, volume = 2017, year = 2017 }
12. Röhrle, O., Sprenger, M., & Schmitt, S. (2017). A two-muscle, continuum-mechanical forward simulation of the upper limb. Biomechanics and Modeling in Mechanobiology, 16(3), 743--762. https://doi.org/10.1007/s10237-016-0850-x
  - BibTeX
  BibTeX
  @article{Roehrle2017a, abstract = {By following the common definition of forward-dynamics simulations, i.e. predicting movement based on (neural) muscle activity, this work describes, for the first time, a forward-dynamics simulation framework of a musculoskeletal system, in which all components are represented as continuous, three-dimensional, volumetric objects. Within this framework, the mechanical behaviour of the entire muscle--tendon complex is modelled as a nonlinear hyperelastic material undergoing finite deformations. The feasibility and the full potential of the proposed forward-dynamics simulation framework is demonstrated on a two-muscle, three-dimensional, continuum-mechanical model of the upper limb. The musculoskeletal model consists of three bones, i.e. humerus, ulna, and radius, an one-degree-of-freedom elbow joint, and an antagonistic muscle pair, i.e. the biceps and triceps brachii, and takes into consideration the contact between the skeletal muscles and the humerus. Numerical studies have shown that the proposed upper limb model is capable of predicting realistic moment arms and muscle forces for the entire range of activation and motion. Within the limitations of the model, the presented simulations provide, for the first time, insights into existing contact forces and their influence on the muscle fibre stretch. Based on the presented simulations, the overall change in fibre stretch is typically less than 3{\%}, despite the fact that the contact forces reach up to 71{\%} of the exerted muscle force. Movement-predicting simulations are achieved by minimising a nonlinear moment equilibrium equation. Based on the forward-dynamics simulation approach, an iterative solution procedures for position-driven (inverse dynamics) and force-driven scenarios have been proposed accordingly. Applying these methodologies to time-dependent scenarios demonstrates that the proposed methods can be linked to state-of-the-art control algorithms predicting time-dependent muscle activation levels based on principles of forward dynamics.}, author = {R{\"o}hrle, O. and Sprenger, M. and Schmitt, S.}, day = 01, doi = {10.1007/s10237-016-0850-x}, issn = {1617-7940}, journal = {Biomechanics and Modeling in Mechanobiology}, month = jun, number = 3, pages = {743--762}, title = {A two-muscle, continuum-mechanical forward simulation of the upper limb}, url = {https://doi.org/10.1007/s10237-016-0850-x}, volume = 16, year = 2017 }
13. Zderic, I., Steinmetz, P., Benneker, L. M., Sprecher, C., Röhrle, O., Windolf, M., Boger, A., & Gueorguiev, B. (2017). Bone cement allocation analysis in artificial cancellous bone structures. Journal of Orthopaedic Translation, 8, 40--48.
  - BibTeX
  BibTeX
  @article{zderic2017bone, author = {Zderic, Ivan and Steinmetz, Philipp and Benneker, Lorin M and Sprecher, Christoph and R{\"o}hrle, Oliver and Windolf, Markus and Boger, Andreas and Gueorguiev, Boyko}, journal = {Journal of orthopaedic translation}, pages = {40--48}, publisher = {Elsevier}, title = {Bone cement allocation analysis in artificial cancellous bone structures}, volume = 8, year = 2017 }
2016
1. Asgharzadeh, P., Özdemir, B., Müller, S. J., Reski, R., & Röhrle, O. (2016). Analysis of confocal microscopy image data of Physcomitrella chloroplasts to reveal adaptation principles leading to structural stability at the nanoscale. PAMM, 16(1), 69--70.
  - BibTeX
  BibTeX
  @article{asgharzadeh2016analysis, author = {Asgharzadeh, Pouyan and {\"O}zdemir, Bugra and M{\"u}ller, Stefanie J and Reski, Ralf and R{\"o}hrle, Oliver}, journal = {PAMM}, number = 1, pages = {69--70}, publisher = {WILEY-VCH Verlag Berlin}, title = {Analysis of confocal microscopy image data of Physcomitrella chloroplasts to reveal adaptation principles leading to structural stability at the nanoscale}, volume = 16, year = 2016 }
2. Chong, S.-Y., & Röhrle, O. (2016). Exploring the Use of Non-Image-Based Ultrasound to Detect the Position of the Residual Femur within a Stump. PloS One, 11(10), e0164583.
  - BibTeX
  BibTeX
  @article{chong2016exploring, author = {Chong, Sook-Yee and R{\"o}hrle, Oliver}, journal = {PloS one}, number = 10, pages = {e0164583}, publisher = {Public Library of Science}, title = {Exploring the Use of Non-Image-Based Ultrasound to Detect the Position of the Residual Femur within a Stump}, volume = 11, year = 2016 }
3. Ghazi-Zahedi, K., Haeufle, D. F., Montúfar, G., Schmitt, S., & Ay, N. (2016). Evaluating morphological computation in muscle and dc-motor driven models of hopping movements. Frontiers in Robotics and AI, 3, 42.
  - BibTeX
  BibTeX
  @article{ghazizahedi2016evaluating, __markedentry = {[syn:]}, author = {Ghazi-Zahedi, Keyan and Haeufle, Daniel FB and Mont{\'u}far, Guido and Schmitt, Syn and Ay, Nihat}, journal = {Frontiers in Robotics and AI}, pages = 42, publisher = {Frontiers}, title = {Evaluating morphological computation in muscle and dc-motor driven models of hopping movements}, volume = 3, year = 2016 }
4. Haeufle, D. F., Bäuerle, T., Steiner, J., Bremicker, L., Schmitt, S., & Bechinger, C. (2016). External control strategies for self-propelled particles: Optimizing navigational efficiency in the presence of limited resources. Physical Review E, 94(1), 012617.
  - BibTeX
  BibTeX
  @article{haeufle2016external, __markedentry = {[syn:6]}, author = {Haeufle, Daniel FB and B{\"a}uerle, Tobias and Steiner, Jakob and Bremicker, Lena and Schmitt, Syn and Bechinger, Clemens}, journal = {Physical Review E}, number = 1, pages = 012617, publisher = {APS}, title = {External control strategies for self-propelled particles: Optimizing navigational efficiency in the presence of limited resources}, volume = 94, year = 2016 }
5. Heidlauf, T., Klotz, T., Rode, C., Altan, E., Bleiler, C., Siebert, T., & Röhrle, O. (2016). A multi-scale continuum model of skeletal muscle mechanics predicting force enhancement based on actin--titin interaction. Biomechanics and Modeling in Mechanobiology, 15(6), 1423--1437.
  - BibTeX
  BibTeX
  @article{heidlauf2016multi, author = {Heidlauf, Thomas and Klotz, Thomas and Rode, Christian and Altan, Ekin and Bleiler, Christian and Siebert, Tobias and R{\"o}hrle, Oliver}, journal = {Biomechanics and modeling in mechanobiology}, number = 6, pages = {1423--1437}, publisher = {Springer Berlin Heidelberg}, title = {A multi-scale continuum model of skeletal muscle mechanics predicting force enhancement based on actin--titin interaction}, volume = 15, year = 2016 }
6. Hochstein, S., Rauschenberger, P., Weigand, B., Siebert, T., Schmitt, S., Schlicht, W., Převorovská, S., & Maršík, F. (2016). Assessment of physical activity of the human body considering the thermodynamic system. Computer Methods in Biomechanics and Biomedical Engineering, 19(9), 923–933. https://doi.org/10.1080/10255842.2015.1076804
  - BibTeX
  BibTeX
  @article{Hochstein2016a, author = {Hochstein, Stefan and Rauschenberger, Philipp and Weigand, Bernhard and Siebert, Tobias and Schmitt, Syn and Schlicht, Wolfgang and Převorovská, Světlana and Maršík, František}, doi = {10.1080/10255842.2015.1076804}, eprint = {https://doi.org/10.1080/10255842.2015.1076804}, journal = {Computer Methods in Biomechanics and Biomedical Engineering}, note = {PMID: 26296149}, number = 9, pages = {923-933}, publisher = {Taylor \& Francis}, title = {Assessment of physical activity of the human body considering the thermodynamic system}, volume = 19, year = 2016 }
7. Röhrle, O., Neumann, V., & Heidlauf, T. (2016). The role of parvalbumin, sarcoplasmatic reticulum calcium pump rate, rates of cross-bridge dynamics, and ryanodine receptor calcium current on peripheral muscle fatigue: a simulation study. Computational and Mathematical Methods in Medicine, 2016.
  - BibTeX
  BibTeX
  @article{rohrle2016role, author = {R{\"o}hrle, Oliver and Neumann, Verena and Heidlauf, Thomas}, journal = {Computational and mathematical methods in medicine}, publisher = {Hindawi}, title = {The role of parvalbumin, sarcoplasmatic reticulum calcium pump rate, rates of cross-bridge dynamics, and ryanodine receptor calcium current on peripheral muscle fatigue: a simulation study}, volume = 2016, year = 2016 }
8. Steinmetz, P., Benneker, L. M., Röhrle, O., Windolf, M., Boger, A., & Gueorguiev, B. (2016). Bone cement allocation analysis in artificial cancellous bone structures. Journal of Orthopaedic Translation, 20, 1e9.
  - BibTeX
  BibTeX
  @article{steinmetz2016bone, author = {Steinmetz, Philipp and Benneker, Lorin M and R{\"o}hrle, Oliver and Windolf, Markus and Boger, Andreas and Gueorguiev, Boyko}, journal = {Journal of Orthopaedic Translation}, pages = {1e9}, title = {Bone cement allocation analysis in artificial cancellous bone structures}, volume = 20, year = 2016 }
2015
1. Bleiler, C., Wagner, A., Stadelmann, V. A., Windolf, M., Köstler, H., Boger, A., Gueorguiev-Rüegg, B., Ehlers, W., & Röhrle, O. (2015). Multiphasic modelling of bone-cement injection into vertebral cancellous bone. International Journal for Numerical Methods in Biomedical Engineering, 31(1), Article 1.
  - BibTeX
  BibTeX
  @article{bleiler2015multiphasic, author = {Bleiler, Christian and Wagner, Arndt and Stadelmann, Vincent A and Windolf, Markus and K{\"o}stler, Harald and Boger, Andreas and Gueorguiev-R{\"u}egg, Boyko and Ehlers, Wolfgang and R{\"o}hrle, Oliver}, journal = {International journal for numerical methods in biomedical engineering}, number = 1, title = {Multiphasic modelling of bone-cement injection into vertebral cancellous bone}, volume = 31, year = 2015 }
2. Chong, S.-Y., Dorow, B., Ramasamy, E., Dennerlein, F., & Röhrle, O. (2015). The use of collision detection to infer multi-camera calibration quality. Frontiers in Bioengineering and Biotechnology, 3, 65.
  - BibTeX
  BibTeX
  @article{chong2015use, author = {Chong, Sook-Yee and Dorow, Beate and Ramasamy, Ellankavi and Dennerlein, Florian and R{\"o}hrle, Oliver}, journal = {Frontiers in Bioengineering and Biotechnology}, pages = 65, publisher = {Frontiers}, title = {The use of collision detection to infer multi-camera calibration quality}, volume = 3, year = 2015 }
3. Kupczik, K., Stark, H., Mundry, R., Neininger, F. T., Heidlauf, T., & Röhrle, O. (2015). Reconstruction of muscle fascicle architecture from iodine-enhanced microCT images: a combined texture mapping and streamline approach. Journal of Theoretical Biology, 382, 34--43.
  - BibTeX
  BibTeX
  @article{kupczik2015reconstruction, author = {Kupczik, Kornelius and Stark, Heiko and Mundry, Roger and Neininger, Fabian T and Heidlauf, Thomas and R{\"o}hrle, Oliver}, journal = {Journal of theoretical biology}, pages = {34--43}, publisher = {Academic Press}, title = {Reconstruction of muscle fascicle architecture from iodine-enhanced microCT images: a combined texture mapping and streamline approach}, volume = 382, year = 2015 }
4. Mordhorst, M., Heidlauf, T., & Röhrle, O. (2015). Predicting electromyographic signals under realistic conditions using a multiscale chemo--electro--mechanical finite element model. Interface Focus, 5(2), 20140076.
  - BibTeX
  BibTeX
  @article{mordhorst2015predicting, author = {Mordhorst, Mylena and Heidlauf, Thomas and R{\"o}hrle, Oliver}, journal = {Interface focus}, number = 2, pages = 20140076, publisher = {The Royal Society}, title = {Predicting electromyographic signals under realistic conditions using a multiscale chemo--electro--mechanical finite element model}, volume = 5, year = 2015 }
5. Rockenfeller, R., Günther, M., Schmitt, S., & Götz, T. (2015). Comparative sensitivity analysis of muscle activation dynamics. Computational and Mathematical Methods in Medicine, 2015.
  - BibTeX
  BibTeX
  @article{rockenfeller2015comparative, __markedentry = {[syn:6]}, author = {Rockenfeller, Robert and G{\"u}nther, Michael and Schmitt, Syn and G{\"o}tz, Thomas}, journal = {Computational and Mathematical Methods in Medicine}, publisher = {Hindawi}, title = {Comparative sensitivity analysis of muscle activation dynamics}, volume = 2015, year = 2015 }
6. Rupp, T., Ehlers, W., Karajan, N., Günther, M., & Schmitt, S. (2015). A forward dynamics simulation of human lumbar spine flexion predicting the load sharing of intervertebral discs, ligaments, and muscles. Biomechanics and Modeling in Mechanobiology, 14(5), 1081--1105.
  - BibTeX
  BibTeX
  @article{rupp2015forward, __markedentry = {[syn:]}, author = {Rupp, TK and Ehlers, W and Karajan, N and G{\"u}nther, M and Schmitt, S}, journal = {Biomechanics and Modeling in Mechanobiology}, number = 5, pages = {1081--1105}, publisher = {Springer}, title = {A forward dynamics simulation of human lumbar spine flexion predicting the load sharing of intervertebral discs, ligaments, and muscles}, volume = 14, year = 2015 }
2014
1. David, S., Schmitt, S., Utz, J., Hub, A., & Schlicht, W. (2014). Navigation within buildings: Novel movement detection algorithms supporting people with visual impairments. Research in Developmental Disabilities, 35(9), 2026–2034. https://doi.org/10.1016/j.ridd.2014.04.032
  - BibTeX
  BibTeX
  @article{David2014a, abstract = {This study aimed at finding simple algorithms to identify three different movements registered by accelerometer and to detect differences in the acceleration signals of people with and without visual impairments. The Tactile Acoustical Navigation and Information Assistant (TANIA) is construed to provide persons suffering from visual impairments support for an independent navigation indoors and outdoors. Attaining this goal, TANIA uses vertical acceleration signal extrema to assess its user's walking distance. This study investigated first the sit-to-stand movement, stumbling and walking up- and down stairs of 25 subjects with visual impairments using TANIA sensor system. The objective was to improve the user's movement detection using sensors to get valid and reliable data. In a second step of the study it was investigated if there is a difference between the above-mentioned movements in people with or without visual impairments (n=10). The acceleration signals of the subjects were compared. Three simple algorithms were found, which are able to separate the movement signals based on accelerometers of the respective daily movements. The second step analysis revealed a detectable difference in the second phase of stumbling (p=.034), where the subjects had to get back into walking forward. No differences in the other acceleration signals were found.}, author = {David, Sina and Schmitt, Syn and Utz, Julianne and Hub, Andreas and Schlicht, Wolfgang}, doi = {https://doi.org/10.1016/j.ridd.2014.04.032}, issn = {0891-4222}, journal = {Research in Developmental Disabilities}, number = 9, pages = {2026 - 2034}, title = {Navigation within buildings: Novel movement detection algorithms supporting people with visual impairments}, url = {http://www.sciencedirect.com/science/article/pii/S0891422214002005}, volume = 35, year = 2014 }
2. Haeufle, D., Günther, M., Bayer, A., & Schmitt, S. (2014). Hill-type muscle model with serial damping and eccentric force--velocity relation. Journal of Biomechanics, 47(6), 1531--1536.
  - BibTeX
  BibTeX
  @article{haeufle2014hilltype, __markedentry = {[syn:]}, author = {Haeufle, DFB and G{\"u}nther, M and Bayer, A and Schmitt, S}, journal = {Journal of Biomechanics}, number = 6, pages = {1531--1536}, publisher = {Elsevier}, title = {Hill-type muscle model with serial damping and eccentric force--velocity relation}, volume = 47, year = 2014 }
3. Haeufle, D., Günther, M., Wunner, G., & Schmitt, S. (2014). Quantifying control effort of biological and technical movements: an information-entropy-based approach. Physical Review E, 89(1), 012716.
  - BibTeX
  BibTeX
  @article{haeufle2014quantifying, __markedentry = {[syn:]}, author = {Haeufle, DFB and G{\"u}nther, M and Wunner, G and Schmitt, S}, journal = {Physical Review E}, number = 1, pages = 012716, publisher = {APS}, title = {Quantifying control effort of biological and technical movements: an information-entropy-based approach}, volume = 89, year = 2014 }
4. Heidlauf, T., & Röhrle, O. (2014). A multiscale chemo-electro-mechanical skeletal muscle model to analyze muscle contraction and force generation for different muscle fiber arrangements. Frontiers in Physiology, 5, 498.
  - BibTeX
  BibTeX
  @article{heidlauf2014multiscale, author = {Heidlauf, Thomas and R{\"o}hrle, Oliver}, journal = {Frontiers in physiology}, pages = 498, publisher = {Frontiers}, title = {A multiscale chemo-electro-mechanical skeletal muscle model to analyze muscle contraction and force generation for different muscle fiber arrangements}, volume = 5, year = 2014 }
5. Kieser, J., Farland, M., Jack, H., Farella, M., Wang, Y., & Rohrle, O. (2014). The role of oral soft tissues in swallowing function: what can tongue pressure tell us? Australian Dental Journal, 59, 155--161.
  - BibTeX
  BibTeX
  @article{kieser2014role, author = {Kieser, JA and Farland, MG and Jack, H and Farella, M and Wang, Y and Rohrle, O}, journal = {Australian dental journal}, pages = {155--161}, title = {The role of oral soft tissues in swallowing function: what can tongue pressure tell us?}, volume = 59, year = 2014 }
6. Ramasamy, E., Dorow, B., Schneider, U., & Roehrle, O. (2014). Simulation-assisted prosthetic design. BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK, 59, S1021--S1021.
  - BibTeX
  BibTeX
  @article{ramasamy2014simulation, author = {Ramasamy, Ellankavi and Dorow, Beate and Schneider, Urs and Roehrle, Oliver}, journal = {BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK}, pages = {S1021--S1021}, publisher = {WALTER DE GRUYTER GMBH GENTHINER STRASSE 13, D-10785 BERLIN, GERMANY}, title = {Simulation-assisted prosthetic design}, volume = 59, year = 2014 }
2013
1. Heidlauf, T., Negro, F., Farina, D., & Röhrle, O. (2013). An integrated model of the neuromuscular system. 2013 6th International IEEE/EMBS Conference on Neural Engineering (NER), 227--230.
  - BibTeX
  BibTeX
  @inproceedings{heidlauf2013integrated, author = {Heidlauf, Thomas and Negro, Francesco and Farina, Dario and R{\"o}hrle, Oliver}, booktitle = {2013 6th International IEEE/EMBS Conference on Neural Engineering (NER)}, organization = {IEEE}, pages = {227--230}, title = {An integrated model of the neuromuscular system}, year = 2013 }
2. Heidlauf, T., & Röhrle, O. (2013). Modeling the chemoelectromechanical behavior of skeletal muscle using the parallel open-source software library OpenCMISS. Computational and Mathematical Methods in Medicine, 2013.
  - BibTeX
  BibTeX
  @article{heidlauf2013modeling, author = {Heidlauf, Thomas and R{\"o}hrle, Oliver}, journal = {Computational and mathematical methods in medicine}, publisher = {Hindawi}, title = {Modeling the chemoelectromechanical behavior of skeletal muscle using the parallel open-source software library OpenCMISS}, volume = 2013, year = 2013 }
3. Karajan, N., Röhrle, O., Ehlers, W., & Schmitt, S. (2013). Linking continuous and discrete intervertebral disc models through homogenisation. Biomechanics and Modeling in Mechanobiology, 12(3), 453--466.
  - BibTeX
  BibTeX
  @article{karajan2013linking, author = {Karajan, N and R{\"o}hrle, O and Ehlers, W and Schmitt, S}, journal = {Biomechanics and modeling in mechanobiology}, number = 3, pages = {453--466}, publisher = {Springer-Verlag}, title = {Linking continuous and discrete intervertebral disc models through homogenisation}, volume = 12, year = 2013 }
4. Schmitt, S., Günther, M., Rupp, T., Bayer, A., & Häufle, D. (2013). Theoretical Hill-type muscle and stability: numerical model and application. Computational and Mathematical Methods in Medicine, 2013, 570878.
  - BibTeX
  BibTeX
  @article{schmitt2013theoretical, abstract = {The construction of artificial muscles is one of the most challenging developments in today's biomedical science. The application of artificial muscles is focused both on the construction of orthotics and prosthetics for rehabilitation and prevention purposes and on building humanoid walking machines for robotics research. Research in biomechanics tries to explain the functioning and design of real biological muscles and therefore lays the fundament for the development of functional artificial muscles. Recently, the hyperbolic Hill-type force-velocity relation was derived from simple mechanical components. In this contribution, this theoretical yet biomechanical model is transferred to a numerical model and applied for presenting a proof-of-concept of a functional artificial muscle. Additionally, this validated theoretical model is used to determine force-velocity relations of different animal species that are based on the literature data from biological experiments. Moreover, it is shown that an antagonistic muscle actuator can help in stabilising a single inverted pendulum model in favour of a control approach using a linear torque generator.}, author = {Schmitt, S and G{\"u}nther, M and Rupp, T and Bayer, A and H{\"a}ufle, D}, date-added = {2014-09-11 19:18:12 +0000}, date-modified = {2014-09-11 19:18:12 +0000}, journal = {Computational and Mathematical Methods in Medicine}, journal-full = {Computational and mathematical methods in medicine}, mesh = {Animals; Artificial Organs; Biomechanical Phenomena; Computer Simulation; Humans; Models, Biological; Muscle Contraction; Muscles}, pages = 570878, pmc = {PMC3844250}, pmid = {24319495}, pst = {ppublish}, title = {Theoretical Hill-type muscle and stability: numerical model and application}, volume = 2013, year = 2013 }
5. Wang, Y. K., Nash, M. P., Pullan, A. J., Kieser, J. A., & Röhrle, O. (2013). Model-based identification of motion sensor placement for tracking retraction and elongation of the tongue. Biomechanics and Modeling in Mechanobiology, 12(2), 383--399.
  - BibTeX
  BibTeX
  @article{wang2013model, author = {Wang, Yikun K and Nash, Martyn P and Pullan, Andrew J and Kieser, Jules A and R{\"o}hrle, Oliver}, journal = {Biomechanics and modeling in mechanobiology}, number = 2, pages = {383--399}, publisher = {Springer-Verlag}, title = {Model-based identification of motion sensor placement for tracking retraction and elongation of the tongue}, volume = 12, year = 2013 }
2012
1. Günther, M., Röhrle, O., Haeufle, D. F., & Schmitt, S. (2012). Spreading out muscle mass within a Hill-type model: a computer simulation study. Computational and Mathematical Methods in Medicine, 2012.
  - BibTeX
  BibTeX
  @article{gunther2012spreading, author = {G{\"u}nther, Michael and R{\"o}hrle, Oliver and Haeufle, Daniel FB and Schmitt, Syn}, journal = {Computational and mathematical methods in medicine}, publisher = {Hindawi}, title = {Spreading out muscle mass within a Hill-type model: a computer simulation study}, volume = 2012, year = 2012 }
2. Haeufle, D. F. B., Taylor, M. D., Schmitt, S., & Geyer, H. (2012). A clutched parallel elastic actuator concept: Towards energy efficient powered legs in prosthetics and robotics. 2012 4th IEEE RAS EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob), 1614–1619. https://doi.org/10.1109/BioRob.2012.6290722
  - BibTeX
  BibTeX
  @inproceedings{Haeufle2012c, author = {{Haeufle}, D. F. B. and {Taylor}, M. D. and {Schmitt}, S. and {Geyer}, H.}, booktitle = {2012 4th IEEE RAS EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob)}, doi = {10.1109/BioRob.2012.6290722}, issn = {2155-1782}, month = {June}, pages = {1614-1619}, title = {A clutched parallel elastic actuator concept: Towards energy efficient powered legs in prosthetics and robotics}, year = 2012 }
3. Haeufle, D., Günther, M., Blickhan, R., & Schmitt, S. (2012). Can quick release experiments reveal the muscle structure? A bionic approach. Journal of Bionic Engineering, 9(2), 211--223.
  - BibTeX
  BibTeX
  @article{haeufle2012quick, __markedentry = {[syn:]}, author = {Haeufle, DFB and G{\"u}nther, M and Blickhan, R and Schmitt, S}, journal = {Journal of Bionic Engineering}, number = 2, pages = {211--223}, publisher = {Springer}, title = {Can quick release experiments reveal the muscle structure? A bionic approach}, volume = 9, year = 2012 }
4. Häufle, D. F. B., Günther, M., Blickhan, R., & Schmitt, S. (2012). Proof of concept: model based bionic muscle with hyperbolic force-velocity relation. Applied Bionics and Biomechanics, 9(3), 276–274.
  - BibTeX
  BibTeX
  @article{haufle2012proof, author = {H{\"a}ufle, Daniel F B and G{\"u}nther, Michael and Blickhan, Reinhard and Schmitt, Syn}, journal = {{Applied Bionics and Biomechanics}}, number = 3, pages = {276-274}, title = {{Proof of concept: model based bionic muscle with hyperbolic force-velocity relation}}, volume = 9, year = 2012 }
5. Mörl, F., Siebert, T., Schmitt, S., Blickhan, R., & Guenther, M. (2012). Electro-mechanical delay in Hill-type muscle models. Journal of Mechanics in Medicine and Biology, 12(05), 1250085.
  - BibTeX
  BibTeX
  @article{morl2012electromechanical, __markedentry = {[syn:6]}, author = {M{\"o}rl, Falk and Siebert, Tobias and Schmitt, Syn and Blickhan, Reinhard and Guenther, Michael}, journal = {Journal of Mechanics in Medicine and Biology}, number = 05, pages = 1250085, publisher = {World Scientific}, title = {Electro-mechanical delay in Hill-type muscle models}, volume = 12, year = 2012 }
6. Röhrle, O., Davidson, J. B., & Pullan, A. J. (2012). A physiologically based, multi-scale model of skeletal muscle structure and function. Frontiers in Physiology, 3, 358.
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  BibTeX
  @article{rohrle2012physiologically, author = {R{\"o}hrle, Oliver and Davidson, John B and Pullan, Andrew J}, journal = {Frontiers in physiology}, pages = 358, publisher = {Frontiers}, title = {A physiologically based, multi-scale model of skeletal muscle structure and function}, volume = 3, year = 2012 }
7. Schmitt, S., Haeufle, D., Blickhan, R., & Günther, M. (2012). Nature as an engineer: one simple concept of a bio-inspired functional artificial muscle. Bioinspiration & Biomimetics, 7(3), 036022.
  - BibTeX
  BibTeX
  @article{schmitt2012nature, __markedentry = {[syn:]}, author = {Schmitt, S and Haeufle, DFB and Blickhan, R and G{\"u}nther, M}, journal = {Bioinspiration \& Biomimetics}, number = 3, pages = 036022, publisher = {IOP Publishing}, title = {Nature as an engineer: one simple concept of a bio-inspired functional artificial muscle}, volume = 7, year = 2012 }
2011
1. Bradley, C., Bowery, A., Britten, R., Budelmann, V., Camara, O., Christie, R., Cookson, A., Frangi, A. F., Gamage, T. B., Heidlauf, T., & others. (2011). OpenCMISS: a multi-physics & multi-scale computational infrastructure for the VPH/Physiome project. Progress in Biophysics and Molecular Biology, 107(1), 32--47.
  - BibTeX
  BibTeX
  @article{bradley2011opencmiss, author = {Bradley, Chris and Bowery, Andy and Britten, Randall and Budelmann, Vincent and Camara, Oscar and Christie, Richard and Cookson, Andrew and Frangi, Alejandro F and Gamage, Thiranja Babarenda and Heidlauf, Thomas and others}, journal = {Progress in biophysics and molecular biology}, number = 1, pages = {32--47}, publisher = {Pergamon}, title = {OpenCMISS: a multi-physics \& multi-scale computational infrastructure for the VPH/Physiome project}, volume = 107, year = 2011 }
2. Häufle, D. F. B., Günther, M., Blickhan, R., & Schmitt, S. (2011). Proof of concept of an artificial muscle: theoretical model, numerical model and hardware experiment. Proceedings of the 12th IEEE International Conference on Rehabilitation Robotics, 8 pages.
  - BibTeX
  BibTeX
  @inproceedings{haufle2011proof, author = {H{\"a}ufle, Daniel F B and G{\"u}nther, Michael and Blickhan, Reinhard and Schmitt, Syn}, booktitle = {{Proceedings of the 12th IEEE International Conference on Rehabilitation Robotics}}, date-added = {2010-06-05 16:09:38 +0200}, date-modified = {2011-06-12 11:38:17 +0200}, pages = {8 pages}, title = {{Proof of concept of an artificial muscle: theoretical model, numerical model and hardware experiment}}, year = 2011 }
3. Rupp, T., & Schmitt, S. (2011). Inverse dynamics of the lower extremities: novel approach considering upper and lower ankle joint axis. Journal of Mechanics in Medicine and Biology, 13 pages.
  - BibTeX
  BibTeX
  @article{rupp2011inverse, author = {Rupp, Tille and Schmitt, Syn}, date-added = {2010-04-09 14:23:43 +0200}, date-modified = {2011-06-12 11:42:07 +0200}, journal = {{Journal of Mechanics in Medicine and Biology}}, pages = {13 pages}, title = {Inverse dynamics of the lower extremities: novel approach considering upper and lower ankle joint axis}, year = 2011 }
4. Schmitt, S., & Günther, M. (2011). Human leg impact: energy dissipation of wobbling masses. Archive of Applied Mechanics, 81(7), 887--897. https://doi.org/10.1007/s00419-010-0458-z
  - BibTeX
  BibTeX
  @article{Schmitt2011a, abstract = {In terrestrial locomotion, the soft-tissue masses of the body undergo damped oscillations following leg impacts with the ground. Appropriate biomechanical models, therefore, describe gross soft-tissue dynamics by “wobbling masses”. We calculated mechanical energy balances of shank and thigh wobbling masses of the stance leg for the first 90 ms after touch-down in human heel-toe running. Thereto, we re-visited a data set on wobbling mass kinematics which had formerly been gained non-invasively by acquiring the motion of grids of lines painted on the skin of the corresponding muscle masses with high-speed cameras. We found frequencies ranging from 3 Hz to 55 Hz and maximum wobbling mass excursions relative to the bone ranging from 3 mm to 4 cm for the centres of mass and from 2.2° to 11.4° for the rotations. The rotational energy balance is practically neutral (±1 J). Usually, there is clearly more energy that is dissipated by wobbling mass movement in horizontal (thigh: <50 J) than in vertical direction (thigh: <15 J). There is less energy dissipated in the shank (horizontal: <10 J, vertical: <5 J). We argue that the energetic costs of separating significant wobbling masses from the skeleton may be over-compensated by avoiding metabolic costs of active impact reduction and by decreasing loads on passive skeletal structures, in particular when distal leg masses are functional, as in humans. Within reasonable biological limits, impacts are known to be even necessary for structural strengthening of bones. Beyond that, impacts might also be useful for stabilising locomotion, both by increasing basins of attraction and by providing simple mechanical signals for control.}, author = {Schmitt, Syn and Günther, Michael}, doi = {10.1007/s00419-010-0458-z}, journal = {Archive of Applied Mechanics}, number = 7, pages = {887--897}, title = {Human leg impact: energy dissipation of wobbling masses}, url = {https://doi.org/10.1007/s00419-010-0458-z}, volume = 81, year = 2011 }
2010
1. Günther, M., & Schmitt, S. (2010). A macroscopic ansatz to deduce the Hill relation. Journal of Theoretical Biology, 263(4), 407--418.
  - BibTeX
  BibTeX
  @article{gunther2010macroscopic, __markedentry = {[syn:6]}, author = {G{\"u}nther, Michael and Schmitt, Syn}, journal = {Journal of Theoretical Biology}, number = 4, pages = {407--418}, publisher = {Elsevier}, title = {A macroscopic ansatz to deduce the Hill relation}, volume = 263, year = 2010 }
2. Häufle, D. F. B., Günther, M., Blickhan, R., & Schmitt, S. (2010). Proof of concept: model based bionic muscle with hyperbolic force-velocity relation. Proceedings of the First International Conference of Applied Biomechanics and Bionics, 7 pages.
  - BibTeX
  BibTeX
  @inproceedings{haufle2010proof, author = {H{\"a}ufle, Daniel F B and G{\"u}nther, Michael and Blickhan, Reinhard and Schmitt, Syn}, booktitle = {{Proceedings of the first International Conference of Applied Biomechanics and Bionics}}, date-added = {2010-09-28 09:53:30 +0200}, date-modified = {2011-06-12 11:38:11 +0200}, pages = {7 pages}, title = {{Proof of concept: model based bionic muscle with hyperbolic force-velocity relation}}, year = 2010 }
3. Röhrle, O. (2010). Simulating the electro-mechanical behavior of skeletal muscles. Computing in Science & Engineering, 12(6), 48--58.
  - BibTeX
  BibTeX
  @article{rohrle2010simulating, author = {Röhrle, Oliver}, journal = {Computing in Science \& Engineering}, number = 6, pages = {48--58}, publisher = {IEEE}, title = {Simulating the electro-mechanical behavior of skeletal muscles}, volume = 12, year = 2010 }
4. Schmid, H., Watton, P., Maurer, M., Wimmer, J., Winkler, P., Wang, Y., Röhrle, O., & Itskov, M. (2010). Impact of transmural heterogeneities on arterial adaptation. Biomechanics and Modeling in Mechanobiology, 9(3), 295--315.
  - BibTeX
  BibTeX
  @article{schmid2010impact, author = {Schmid, H and Watton, PN and Maurer, MM and Wimmer, J and Winkler, P and Wang, YK and R{\"o}hrle, O and Itskov, M}, journal = {Biomechanics and modeling in mechanobiology}, number = 3, pages = {295--315}, publisher = {Springer-Verlag}, title = {Impact of transmural heterogeneities on arterial adaptation}, volume = 9, year = 2010 }
2009
1. Melnyk, M., Schloz, C., Schmitt, S., & Gollhofer, A. (2009). Neuromuscular ankle joint stabilisation after 4-weeks WBV training. International Journal of Sports Medicine, 30(6), 461--466. https://doi.org/10.1055/s-0028-1112141
  - BibTeX
  BibTeX
  @article{melnyk2009neuromuscular, abstract = {Whole body vibration (WBV) training is increasingly implemented in prevention programs as well as in rehabilitation protocols but evidence for beneficial effects of WBV training over several weeks on ankle joint stabilisation is lacking. The purpose of the study was to investigate the effects of 4-weeks WBV training on reflex activity of the long peroneal and tibialis anterior muscles and on the duration of ankle inversion movement in response to an unexpected combined 24 degrees inversion 15 degrees plantar flexion ankle joint motion. Twenty-six healthy subjects were divided into an intervention group (n=16) and a control group (n=10). The intervention group trained thrice weekly for 3 min on a unidirectional oscillating vibration platform (30 Hz, 4 mm amplitude). Pre and post intervention reflex activity were measured and the duration of ankle joint movement was calculated by vertical ground reaction forces. After four weeks of WBV training no significant changes were found in latencies and reflex activity in both muscles in response to ankle sprain simulation. Similar results were observed for the time of ankle inversion motion. Based on the present results, it is unlikely that 4-weeks WBV training has beneficial effects on ankle joint stability in the case of an ankle inversion motion.}, address = {Department of Sport and Sport Science, University of Freiburg, Germany. mark.melnyk@unibas.ch}, au = {Melnyk, M and Schloz, C and Schmitt, S and Gollhofer, A}, author = {Melnyk, M and Schloz, C and Schmitt, S and Gollhofer, A}, bdsk-url-1 = {http://dx.doi.org/10.1055/s-0028-1112141}, crdt = {2009/03/12 09:00}, da = {20090526}, date-added = {2009-11-14 16:02:17 +0100}, date-modified = {2010-01-11 09:40:03 +0100}, dcom = {20090811}, dep = {20090310}, doi = {10.1055/s-0028-1112141}, edat = {2009/03/12 09:00}, issn = {1439-3964 (Electronic)}, jid = {8008349}, journal = {International Journal of Sports Medicine}, jt = {International journal of sports medicine}, language = {eng}, mhda = {2009/08/12 09:00}, number = 6, own = {NLM}, pages = {461--466}, phst = {2009/03/10 {$[$}epublish{$]$}; 2009/03/10 {$[$}aheadofprint{$]$}}, pl = {Germany}, pmid = {19277942}, pst = {ppublish}, pt = {Journal Article; Randomized Controlled Trial}, sb = {IM}, so = {Int J Sports Med. 2009 Jun;30(6):461-6. Epub 2009 Mar 10.}, stat = {MEDLINE}, title = {{Neuromuscular ankle joint stabilisation after 4-weeks WBV training}}, volume = 30, year = 2009 }
2. Röhrle, O., Waddell, J. N., Foster, K. D., Saini, H., & Pullan, A. J. (2009). Using a motion-capture system to record dynamic articulation for application in CAD/CAM software. Journal of Prosthodontics: Implant, Esthetic and Reconstructive Dentistry, 18(8), 703--710.
  - BibTeX
  BibTeX
  @article{rohrle2009using, author = {R{\"o}hrle, Oliver and Waddell, J Neil and Foster, Kylie D and Saini, Harnoor and Pullan, Andrew J}, journal = {Journal of Prosthodontics: Implant, Esthetic and Reconstructive Dentistry}, number = 8, pages = {703--710}, publisher = {Blackwell Publishing Inc Malden, USA}, title = {Using a motion-capture system to record dynamic articulation for application in CAD/CAM software}, volume = 18, year = 2009 }
3. Saini, H., Wadell, J., Pullan, A., & Röhrle, O. (2009). Automatically generating subject-specific functional tooth surfaces using virtual mastication. Annals of Biomedical Engineering, 37(8), 1646--1653.
  - BibTeX
  BibTeX
  @article{saini2009automatically, author = {Saini, H and Wadell, JN and Pullan, AJ and R{\"o}hrle, Oliver}, journal = {Annals of biomedical engineering}, number = 8, pages = {1646--1653}, publisher = {Springer US}, title = {Automatically generating subject-specific functional tooth surfaces using virtual mastication}, volume = 37, year = 2009 }
4. Schmitt, S., Melnyk, M., Alt, W., & Gollhofer, A. (2009). Novel approach for a precise determination of short-time intervals in ankle sprain experiments. Journal of Biomechanics, 42, 2823–2825. https://doi.org/10.1016/j.jbiomech.2009.08.015
  - BibTeX
  BibTeX
  @article{schmitt2009novel, abstract = {The etiology of ankle sprain injury is still under debate. Therefore, diagnoses of ankle inversion experiments play an important role. Recent studies stress the importance of exact time measurements due to the short inversion period of around 70ms. This paper presents a novel approach using the vertical ground reaction force (vGRF) to determine the short-time intervals in ankle sprain experiments, which are present in the form of short periods from the beginning of the movement to its end and short latencies to following signals, e.g. EMG onset of peroneal muscles. We compare our method to electrogoniometry at the ankle which is considered as the gold standard. During the inversion movement the kinematic action at the ankle can be measured with electrogoniometry, whereas the vGRF quantifies the vertical dynamic reaction of the tested subject entirely. We observe a difference of DeltaT(f,0-->g,0)=10+/-0.5ms between the first observable vGRF response and the first observable electrogoniometer response following platform release. The end of the ankle inversion measured with electrogoniometry is DeltaT(f,1-->g,1)=3+/-0.5ms later than the maximal vGRF peak. The potential supplementary (mechanical) information of this novel approach compared to electrogoniometry and its ease of use, may be not only interesting for researchers when studying ankle sprain simulations but also for clinicians when testing functional ankle stability.}, address = {Institut fur Sport- und Bewegungswissenschaft, Universitat Stuttgart, Allmandring 28, D-70569 Stuttgart, Germany.}, author = {Schmitt, S and Melnyk, M and Alt, W and Gollhofer, A}, bdsk-url-1 = {http://dx.doi.org/10.1016/j.jbiomech.2009.08.015}, crdt = {2009/09/22 06:00}, da = {20090921}, date-added = {2009-11-14 16:02:17 +0100}, date-modified = {2010-01-11 09:42:14 +0100}, dep = {20090917}, doi = {10.1016/j.jbiomech.2009.08.015}, edat = {2009/09/22 06:00}, issn = {1873-2380 (Electronic)}, jid = {0157375}, journal = {{Journal of Biomechanics}}, jt = {Journal of biomechanics}, language = {ENG}, mhda = {2009/09/22 06:00}, own = {NLM}, pages = {2823-2825}, phst = {2008/04/29 {$[$}received{$]$}; 2009/06/30 {$[$}revised{$]$}; 2009/08/11 {$[$}accepted{$]$}}, pii = {S0021-9290(09)00455-2}, pmid = {19766223}, pst = {aheadofprint}, pt = {JOURNAL ARTICLE}, so = {J Biomech. 2009 Sep 17.}, stat = {Publisher}, title = {Novel approach for a precise determination of short-time intervals in ankle sprain experiments.}, volume = 42, year = 2009 }
2008
1. Röhrle, O., Davidson, J. B., & Pullan, A. J. (2008). Bridging scales: a three-dimensional electromechanical finite element model of skeletal muscle. SIAM Journal on Scientific Computing, 30(6), 2882--2904.
  - BibTeX
  BibTeX
  @article{rohrle2008bridging, author = {R{\"o}hrle, Oliver and Davidson, John B and Pullan, Andrew J}, journal = {SIAM Journal on Scientific Computing}, number = 6, pages = {2882--2904}, publisher = {Society for Industrial and Applied Mathematics}, title = {Bridging scales: a three-dimensional electromechanical finite element model of skeletal muscle}, volume = 30, year = 2008 }
2. Xu, W., Bronlund, J., Potgieter, J., Foster, K., Röhrle, O., Pullan, A., & Kieser, J. (2008). Review of the human masticatory system and masticatory robotics. Mechanism and Machine Theory, 43(11), 1353--1375.
  - BibTeX
  BibTeX
  @article{xu2008review, author = {Xu, WL and Bronlund, JE and Potgieter, J and Foster, KD and R{\"o}hrle, O and Pullan, AJ and Kieser, JA}, journal = {Mechanism and Machine Theory}, number = 11, pages = {1353--1375}, publisher = {Pergamon}, title = {Review of the human masticatory system and masticatory robotics}, volume = 43, year = 2008 }
2007
1. Kim, J. H., Davidson, J. B., Röhrle, O., Soboleva, T. K., & Pullan, A. J. (2007). Anatomically based lower limb nerve model for electrical stimulation. Biomedical Engineering Online, 6(1), 48.
  - BibTeX
  BibTeX
  @article{kim2007anatomically, author = {Kim, Juliana HK and Davidson, John B and R{\"o}hrle, Oliver and Soboleva, Tanya K and Pullan, Andrew J}, journal = {Biomedical engineering online}, number = 1, pages = 48, publisher = {BioMed Central}, title = {Anatomically based lower limb nerve model for electrical stimulation}, volume = 6, year = 2007 }
2. Röhrle, O., & Pullan, A. J. (2007). Three-dimensional finite element modelling of muscle forces during mastication. Journal of Biomechanics, 40(15), 3363--3372.
  - BibTeX
  BibTeX
  @article{rohrle2007three, author = {R{\"o}hrle, Oliver and Pullan, Andrew J}, journal = {Journal of biomechanics}, number = 15, pages = {3363--3372}, publisher = {Elsevier}, title = {Three-dimensional finite element modelling of muscle forces during mastication}, volume = 40, year = 2007 }
3. Schmid, H., Nash, M., Young, A., Röhrle, O., & Hunter, P. (2007). A computationally efficient optimization kernel for material parameter estimation procedures. Journal of Biomechanical Engineering, 129(2), 279--283.
  - BibTeX
  BibTeX
  @article{schmid2007computationally, author = {Schmid, H and Nash, MP and Young, AA and R{\"o}hrle, O and Hunter, PJ}, journal = {Journal of biomechanical engineering}, number = 2, pages = {279--283}, publisher = {American Society of Mechanical Engineers}, title = {A computationally efficient optimization kernel for material parameter estimation procedures}, volume = 129, year = 2007 }
4. Schmitt, S., Kettler, A., Mutschler, H., Schmidt, H., Ruder, H., & Wilke, H.-J. (2007). Simulation von Störungen auf die Lumbalwirbelsäule - eine Projektskizze. In VDI Berichte Nr. (Ed.), Humanschwingungen (pp. 277–291). Düsseldorf, VDI.
  - BibTeX
  BibTeX
  @incollection{schmitt2007simulation, author = {Schmitt, Syn and Kettler, Anette and Mutschler, Helmut and Schmidt, Hendrik and Ruder, Hanns and Wilke, Hans-Joachim}, booktitle = {Humanschwingungen}, date-added = {2009-11-02 21:29:53 +0100}, date-modified = {2010-01-11 09:40:48 +0100}, editor = {{VDI Berichte Nr. 2002}}, pages = {277-291}, publisher = {D{\"u}sseldorf, VDI}, title = {{Simulation von St{\"o}rungen auf die Lumbalwirbels{\"a}ule - eine Projektskizze}}, year = 2007 }
2006
1. Kim, S. D., Lee, C.-O., Manteuffel, T. A., McCormick, S. F., & Röhrle, O. (2006). First-order system least squares for the Oseen equations. Numerical Linear Algebra with Applications, 13(7), 523--542.
  - BibTeX
  BibTeX
  @article{kim2006first, author = {Kim, Sang Dong and Lee, Chang-Ock and Manteuffel, Thomas A and McCormick, Stephen F and R{\"o}hrle, Oliver}, journal = {Numerical Linear Algebra with Applications}, number = 7, pages = {523--542}, publisher = {John Wiley \& Sons, Ltd. Chichester, UK}, title = {First-order system least squares for the Oseen equations}, volume = 13, year = 2006 }
2. Manteuffel, T. A., McCormick, S. F., & Röhrle, O. (2006). Projection multilevel methods for quasilinear elliptic partial differential equations: Theoretical results. SIAM Journal on Numerical Analysis, 44(1), 139--152.
  - BibTeX
  BibTeX
  @article{manteuffel2006projection, author = {Manteuffel, Thomas A and McCormick, Stephen F and R{\"o}hrle, Oliver}, journal = {SIAM journal on numerical analysis}, number = 1, pages = {139--152}, publisher = {Society for Industrial and Applied Mathematics}, title = {Projection multilevel methods for quasilinear elliptic partial differential equations: Theoretical results}, volume = 44, year = 2006 }
3. Manteuffel, T. A., McCormick, S. F., Röhrle, O., & Ruge, J. (2006). Projection multilevel methods for quasilinear elliptic partial differential equations: numerical results. SIAM Journal on Numerical Analysis, 44(1), 120--138.
  - BibTeX
  BibTeX
  @article{manteuffel2006projection, author = {Manteuffel, Thomas A and McCormick, Stephen F and R{\"o}hrle, Oliver and Ruge, John}, journal = {SIAM journal on numerical analysis}, number = 1, pages = {120--138}, publisher = {Society for Industrial and Applied Mathematics}, title = {Projection multilevel methods for quasilinear elliptic partial differential equations: numerical results}, volume = 44, year = 2006 }

Book Chapter or Edited Books

Reski R, Özdemir B, Asgharzadeh P, Birkhold A, Röhrle O. The plastid skeleton: a source of ideas in the nano range. In: Biomimetics for Architecture Learning from Nature. Birkhäuser; 2019. p. 163–6. (Biomimetics for Architecture. Learning from Nature).
- BibTeX
BibTeX
@incollection{Oezdemir2019, author = {Reski, Ralf and Özdemir, Bugra and Asgharzadeh, Pouyan and Birkhold, Annette and Röhrle, Oliver}, booktitle = {Biomimetics for Architecture. Learning from Nature}, pages = {163-166}, publisher = {Birkhäuser}, title = {The plastid skeleton: a source of ideas in the nano range}, year = 2019 }
Röhrle O. Skeletal Muscle Modelling. Encyclopaedia for Continuum Mechanics Section Biomechanics. 2018;
- BibTeX
BibTeX
@article{rohrle2018skeletal, author = {Röhrle, Oliver}, journal = {Encyclopaedia for Continuum Mechanics Section Biomechanics}, title = {Skeletal Muscle Modelling}, year = 2018 }
Asgharzadeh P, Özdemir B, Müller SJ, Röhrle O, Reski R. Analysis of Physcomitrella chloroplasts to reveal adaptation principles leading to structural stability at the nano-scale. In: Biomimetic Research for Architecture and Building Construction. Springer, Cham; 2016. p. 261--275. (Biomimetic Research for Architecture and Building Construction).
- BibTeX
BibTeX
@incollection{asgharzadeh2016analysis, author = {Asgharzadeh, Pouyan and {\"O}zdemir, Bugra and M{\"u}ller, Stefanie J and R{\"o}hrle, Oliver and Reski, Ralf}, booktitle = {Biomimetic Research for Architecture and Building Construction}, pages = {261--275}, publisher = {Springer, Cham}, title = {Analysis of Physcomitrella chloroplasts to reveal adaptation principles leading to structural stability at the nano-scale}, year = 2016 }
Betz O, Birkhold A, Caliaro M, Eggs B, Mader A, Knippers J, et al. Adaptive stiffness and joint-free kinematics: actively actuated rod-shaped structures in plants and animals and their biomimetic potential in architecture and engineering. In: Biomimetic Research for Architecture and Building Construction. Springer, Cham; 2016. p. 135--167. (Biomimetic Research for Architecture and Building Construction).
- BibTeX
BibTeX
@incollection{betz2016adaptive, author = {Betz, Oliver and Birkhold, Annette and Caliaro, Marco and Eggs, Benjamin and Mader, Anja and Knippers, Jan and R{\"o}hrle, Oliver and Speck, Olga}, booktitle = {Biomimetic Research for Architecture and Building Construction}, pages = {135--167}, publisher = {Springer, Cham}, title = {Adaptive stiffness and joint-free kinematics: actively actuated rod-shaped structures in plants and animals and their biomimetic potential in architecture and engineering}, year = 2016 }
Schmitt S, Lechler A, Röhrle O. Modellierung und Simulation als Werkzeug für das Design von Mensch-Maschine-Systemen: Modellierung und Simulation als Werkzeug für das Design von Mensch-Maschine-Systemen. In Berlin: Springer Vieweg; 2015. p. 178–84.
- BibTeX
BibTeX
@incollection{SchmittLechlerRoehrle2015, __markedentry = {[xtl:6]}, address = {Berlin}, author = {Schmitt, S. and Lechler, A. and Röhrle, O.}, pages = {178-184}, publisher = {Springer Vieweg}, title = {Modellierung und Simulation als Werkzeug für das Design von Mensch-Maschine-Systemen: Modellierung und Simulation als Werkzeug für das Design von Mensch-Maschine-Systemen}, year = 2015 }
Schmitt S, Haeufle D. Mechanics and thermodynamics of biological muscle--a simple model approach. In: Soft Robotics. Springer; 2015. p. 134--144. (Soft Robotics).
- BibTeX
BibTeX
@incollection{schmitt2015mechanics, __markedentry = {[syn:]}, author = {Schmitt, Syn and Haeufle, Daniel}, booktitle = {Soft Robotics}, pages = {134--144}, publisher = {Springer}, title = {Mechanics and thermodynamics of biological muscle--a simple model approach}, year = 2015 }
Röhrle O, Sprenger M, Ramasamy E, Heidlauf T. Multiscale skeletal muscle modeling: from cellular level to a multi-segment skeletal muscle model of the upper limb. In: Computer models in biomechanics. Springer, Dordrecht; 2013. p. 103--116. (Computer models in biomechanics).
- BibTeX
BibTeX
@incollection{rohrle2013multiscale, author = {R{\"o}hrle, Oliver and Sprenger, Michael and Ramasamy, Ellankavi and Heidlauf, Thomas}, booktitle = {Computer models in biomechanics}, pages = {103--116}, publisher = {Springer, Dordrecht}, title = {Multiscale skeletal muscle modeling: from cellular level to a multi-segment skeletal muscle model of the upper limb}, year = 2013 }
Wang Y, Gamage TPB, Nielsen PM, Röhrle O, Nash MP. Identification of tongue muscle fibre group contraction from MR images. In: Computational Biomechanics for Medicine. Springer, New York, NY; 2013. p. 185--196. (Computational Biomechanics for Medicine).
- BibTeX
BibTeX
@incollection{wang2013identification, author = {Wang, Yikun and Gamage, Thiranja P Babarenda and Nielsen, Poul MF and R{\"o}hrle, Oliver and Nash, Martyn P}, booktitle = {Computational Biomechanics for Medicine}, pages = {185--196}, publisher = {Springer, New York, NY}, title = {Identification of tongue muscle fibre group contraction from MR images}, year = 2013 }
Röhrle O, Köstler H, Loch M. Segmentation of skeletal muscle fibres for applications in computational skeletal muscle mechanics. In: Computational Biomechanics for Medicine. Springer, New York, NY; 2011. p. 107--117. (Computational Biomechanics for Medicine).
- BibTeX
BibTeX
@incollection{rohrle2011segmentation, author = {R{\"o}hrle, O and K{\"o}stler, H and Loch, M}, booktitle = {Computational Biomechanics for Medicine}, pages = {107--117}, publisher = {Springer, New York, NY}, title = {Segmentation of skeletal muscle fibres for applications in computational skeletal muscle mechanics}, year = 2011 }
Ehlers W, Markert B, Röhrle O, editors. Biomechanics. GAMM-Mitteilungen; 2009.
- BibTeX
BibTeX
@book{ehlers2009biomechanics, editor = {Ehlers, Wolfgang and Markert, Bernd and R\"ohrle, Oliver}, publisher = {GAMM-Mitteilungen}, title = {Biomechanics}, year = 2009 }
Wangerin M, Schmitt S, Stapelfeldt B, Gollhofer A. Inverse Dynamics in Cycling Performance. In: Buzug T, editor. Advances in Medical Engineering. Springer; 2007. p. 329--334. (Buzug T, editor. Advances in Medical Engineering).
- BibTeX
BibTeX
@incollection{wangerin2007inverse, abstract = {Joint reaction forces and moments are of great interest for cyclists, coaches, therapists and medics because they give information about muscular effort and therefore cycling technique. The objective of this study is to examine the influence of pedalling rate and power on joint moments. An own mechanical construction was used to measure pedal forces, kinematic data was recorded and joint moment calculations were solved on a computer for ankle, knee and hip with help of a link segment model. Results show an increase of moments with increase of power and decrease of pedal rate. }, author = {Wangerin, Malte and Schmitt, Syn and Stapelfeldt, Bj{\~A}¶rn and Gollhofer, Albert}, booktitle = {Advances in Medical Engineering}, date-added = {2007-12-03 21:11:52 +0100}, date-modified = {2009-11-02 21:21:32 +0100}, editor = {Buzug, Thorsten}, pages = {329--334}, publisher = {Springer}, title = {Inverse Dynamics in Cycling Performance}, year = 2007 }

Patents

Kleiner B, Röhrle O, Hülsmann A, Röhrle A. Mobile radar-basierte Umgebungsvermessung unter Anwendung von Sensorfusion mittels Intrarotkamera und Inertialsensorik. 2015.
- BibTeX
BibTeX
@patent{noauthororeditor2015mobile, author = {Kleiner, Bernhard and Röhrle, Oliver and Hülsmann, Axel and Röhrle, Adrian}, title = {Mobile radar-basierte Umgebungsvermessung unter Anwendung von Sensorfusion mittels Intrarotkamera und Inertialsensorik}, year = 2015 }
Röhrle O. Verfahren zur Bestimmung einer Beißkraft. 2014.
- BibTeX
BibTeX
@misc{rohrle2014verfahren, author = {R{\"o}hrle, Oliver}, title = {Verfahren zur Bestimmung einer Bei{\ss}kraft}, year = 2014 }
Smith NP, Budgett DM, Hunter PJ, Malcolm DTK, Cheng LK-W, Nash MP, et al. Biophysical virtual model database and applications. 2010.
- BibTeX
BibTeX
@misc{smith2010biophysical, author = {Smith, Nicolas Peter and Budgett, David Mortimer and Hunter, Peter John and Malcolm, Duane Tearaitoa Kingwell and Cheng, Leo Koon-Wah and Nash, Martyn Peter and Nielsen, Poul Michael Fonss and Pullan, Andrew John and Young, Alistair Andrew and Roehrle, Oliver and others}, note = {US Patent App. 12/375,354}, title = {Biophysical virtual model database and applications}, year = 2010 }
Blickhan R, Günther M, Schmitt S. Vorrichtung zur Nachbildung des Bewegungsverhaltens eines natürlichen Muskels. Europäisches Patentamt; 2010. Report No.: PCT/DE 2010/000160.
- BibTeX
BibTeX
@techreport{blickhan2010vorrichtung, author = {Blickhan, Reinhard and G{\"u}nther, Michael and Schmitt, Syn}, date-added = {2009-11-14 17:54:03 +0100}, date-modified = {2010-04-09 14:13:15 +0200}, institution = {{Europ{\"a}isches Patentamt}}, number = {PCT/DE 2010/000160}, title = {{Vorrichtung zur Nachbildung des Bewegungsverhaltens eines nat\"urlichen Muskels}}, year = 2010 }
Blickhan R, Günther M, Schmitt S. Vorrichtung zur Nachbildung des Bewegungsverhaltens eines natürlichen Muskels. Deutsches Patent- und Markenamt; 2008. Report No.: DE 10 2008 058 604.8.
- BibTeX
BibTeX
@techreport{blickhan2008vorrichtung, author = {Blickhan, Reinhard and G{\"u}nther, Michael and Schmitt, Syn}, date-added = {2010-04-09 14:12:05 +0200}, date-modified = {2010-04-09 14:12:05 +0200}, institution = {{Deutsches Patent- und Markenamt}}, number = {DE 10 2008 058 604.8}, title = {{Vorrichtung zur Nachbildung des Bewegungsverhaltens eines nat\"urlichen Muskels}}, year = 2008 }

Completed PhD Thesis

Chair for Continuum Biomechanics and Mechanobiology

Asgharzadeh, Pouyan (2020): Image-based analysis of biological network structures using machine learning and continuum mechanics, Dissertation, University of Stuttgart [Download PDF, ISBN 978-3-946412-05-2, DOI: 10.18419/opus-11154]
Mordhorst, Mylena (2020): Towards a fast and stable dynamic skeletal muscle model, Dissertation, University of Stuttgart [Download PDF, ISBN 978-3-946412-04-5, DOI: 10.18419/opus-11159]
Hessenthaler, Andreas (2020): Multilevel convergence analysis: parallel-in-time integration for fluid-structure interaction problems with applications in cardiac flow modeling, Dissertation, University of Stuttgart [Download PDF, ISBN 978-3-946412-03-8, DOI: 10.18419/opus-11260]
Ramasamy, Ellankavi (2019): A modelling-simulation-analysis workflow for investigating socket-stump interaction, Dissertation, University of Stuttgart [Download PDF, ISBN 978-3-946412-02-1, DOI: 10.18419/opus-10559]
Heidlauf, Thomas (2015): Chemo-electro-mechanical modelling of the neuromuscular system, Dissertation, University of Stuttgart [Download PDF, ISBN 978-3-946412-00-7, DOI: 10.18419/opus-658]
Wang, Yikun (2014): Modelling Tongue Mechanics, Dissertation, University of Auckland, New Zealand [Download PDF]
Davidson, John (2009): Biophysical Modelling of Skeletal Muscle, Dissertation, University of Auckland, New Zealand [Download PDF]

Publications

International, peer-reviewed Publications

2021

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2020

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2019

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2018

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2017

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2016

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2015

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2014