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Bleiler, Christian

Christian Bleiler

Dr.-Ing.

Lecturer
Senior Scientist

Contact

+49 711 685 65853
Email

Pfaffenwaldring 5a
70569 Stuttgart
Deutschland
Room: 02.015

Subject

Continuum (bio)mechanics
- Modelling of deformable bodies
- Variational principles
- Constitutive material theory
- Modelling internally constrained materials

Multiscale mechanics and homogenisation theory
- Material modelling across scales
- Analytical homogenisation methods
- Tangent-second-order methods for hyperelastic composites
- Network models for fibrous microstructures

Skeletal muscle and soft tissue mechanics
- Multiscale constitutive modelling of skeletal muscle tissue
- Collagen fibre mechanics
- Bottom-up estimation of macroscopic material properties
- Statistical description of tissue microstructures

Porous media mechanics
- Modelling multiphase materials with different states of matter
- Modelling fluid-saturated porous media
- Modelling medical injection processes (vertebroplasty)
- Image-based permeability estimation

Publications

2026
1. Rosin, D., Kässinger, J., Yu, X., Sedlmair, M., Avci, O., Bleiler, C., & Röhrle, O. (2026). PerSiVal: deep neural networks for pervasive simulation of an activation-driven continuum-mechanical upper limb model. Medical & Biological Engineering & Computing. https://doi.org/10.1007/s11517-026-03519-x
  - BibTeX
  BibTeX
  @article{Rosin2026, abstract = {This paper introduces a novel densely connected neural network architecture designed for the pervasive visualisation of musculoskeletal system simulations. These simulations are built upon continuum-mechanical frameworks, which effectively integrate the diverse structural and physiological properties of the musculoskeletal system. A significant drawback of continuum-mechanical musculoskeletal models is their substantial computational resource requirement, making them difficult to transfer to/visualise the results on resource-poor systems like augmented reality or mobile devices. Such technologies, however, will be crucial for future advancements in human-machine interaction, surgical support tools, or physiotherapy. We use an activation-driven five-muscle continuum-mechanical upper limb model to obtain the activation-induced deformations of the respective muscles. Exemplified on the m. biceps brachii, we fit a sparse grid surrogate to capture the surface deformation and train a deep learning model that is subsequently used in our real-time visualisation. Based on the activation levels of the five muscles, the result of our trained neural network leads to an average positional error of 0.97{\textpm}0.16 mm, or 0.57{\textpm}0.10{\%} for the 2809 mesh nodes of the m. biceps brachii's surface. With the novel deep neural network model, we achieved evaluation times for the m. biceps brachii's surface deformation of 9.88 ms on CPU-only architectures and 3.48 ms on architectures with GPU support. This leads to theoretical frame rates of 101 fps and 287 fps, respectively. The combination of surrogates and deep neural networks presented here succeeds as a proof-of-concept for real-time visualisation of a complex musculoskeletal system model, and does not rely on the inherent characteristics of the musculoskeletal system, and, hence, is also applicable to other real-time visualisations of complex meshed models in other applications.}, author = {Rosin, David and K{\"a}ssinger, Johannes and Yu, Xingyao and Sedlmair, Michael and Avci, Okan and Bleiler, Christian and R{\"o}hrle, Oliver}, day = 03, doi = {10.1007/s11517-026-03519-x}, editor = {Nature, Springer}, issn = {1741-0444}, journal = {Medical {\&} Biological Engineering {\&} Computing}, month = {02}, title = {PerSiVal: deep neural networks for pervasive simulation of an activation-driven continuum-mechanical upper limb model}, url = {https://doi.org/10.1007/s11517-026-03519-x}, year = 2026 }
2024
1. Villota-Narvaez, Y., Bleiler, C., & Röhrle, O. (2024). Data sharing in modeling and simulation of biomechanical systems in interdisciplinary environments. GAMM-Mitteilungen, 47, Article 2. https://doi.org/10.1002/gamm.202370006
  - BibTeX
  BibTeX
  @article{https://doi.org/10.1002/gamm.202370006, author = {Villota-Narvaez, Yesid and Bleiler, Christian and Röhrle, Oliver}, doi = {https://doi.org/10.1002/gamm.202370006}, eprint = {https://onlinelibrary.wiley.com/doi/pdf/10.1002/gamm.202370006}, journal = {GAMM-Mitteilungen}, number = 2, pages = {e202370006}, title = {Data sharing in modeling and simulation of biomechanical systems in interdisciplinary environments}, url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/gamm.202370006}, volume = 47, year = 2024 }
2022
1. Bleiler, C., & Röhrle, O. (2022). Classification of Biomechanical Models: The Wrong Battle Between Phenomenological and Structural Approaches, the Partly Underestimated Strength of Phenomenology and Challenges for Future (Clinical) Applications. In Solid (Bio) mechanics: Challenges of the Next Decade (pp. 335–352). Springer. https://doi.org/10.1007/978-3-030-92339-6_14
  - BibTeX
  BibTeX
  @incollection{bleiler2022classification, author = {Bleiler, Christian and R{\"o}hrle, Oliver}, booktitle = {Solid (Bio) mechanics: Challenges of the Next Decade}, doi = {https://doi.org/10.1007/978-3-030-92339-6_14}, isbn = {978-3-030-92338-9}, pages = {335--352}, publisher = {Springer}, title = {Classification of Biomechanical Models: The Wrong Battle Between Phenomenological and Structural Approaches, the Partly Underestimated Strength of Phenomenology and Challenges for Future (Clinical) Applications}, year = 2022 }
2. Bleiler, C., & Röhrle, O. (2022). Strain Measures and Energies for Crimped Fibres and Novel Analytical Expressions for Fibre Populations: Ingredients for Structural Fibre Network Models. Journal of Elasticity, 150, 401–448. https://doi.org/10.1007/s10659-022-09920-5
  - BibTeX
  BibTeX
  @article{bleiler2022strain, author = {Bleiler, Christian and R{\"o}hrle, Oliver}, doi = {https://doi.org/10.1007/s10659-022-09920-5}, journal = {Journal of Elasticity}, pages = {401-448}, publisher = {Springer}, title = {Strain Measures and Energies for Crimped Fibres and Novel Analytical Expressions for Fibre Populations: Ingredients for Structural Fibre Network Models}, volume = 150, year = 2022 }
2021
1. Trivedi, Z., Bleiler, C., Gehweiler, D., Gueorguiev-Rüegg, B., Ricken, T., Wagner, A., & Röhrle, O. (2021). Simulating vertebroplasty: A biomechanical challenge. Pamm, 20, e202000313. https://doi.org/10.1002/pamm.202000313
  - BibTeX
  BibTeX
  @article{Trivedi2021, author = {Trivedi, Zubin and Bleiler, Christian and Gehweiler, Dominic and Gueorguiev-R{\"u}egg, Boyko and Ricken, Tim and Wagner, Arndt and R{\"o}hrle, Oliver}, doi = {https://doi.org/10.1002/pamm.202000313}, journal = {PAMM}, pages = {e202000313}, title = {Simulating vertebroplasty: A biomechanical challenge}, volume = 20, year = 2021 }
2. Klotz, T., Bleiler, C., & Röhrle, O. (2021). A Physiology-Guided Classification of Active-Stress and Active-Strain Approaches for Continuum-Mechanical Modeling of Skeletal Muscle Tissue. Frontiers in Physiology, 12, 1–13. https://doi.org/10.3389/fphys.2021.685531
  - BibTeX
  BibTeX
  @article{Klotz2021, author = {Klotz, Thomas and Bleiler, Christian and R\"{o}hrle, Oliver}, doi = {10.3389/fphys.2021.685531}, journal = {Frontiers in Physiology}, pages = {1-13}, title = {A {P}hysiology-{G}uided {C}lassification of {A}ctive-{S}tress and {A}ctive-{S}train {A}pproaches for {C}ontinuum-{M}echanical {M}odeling of {S}keletal {M}uscle {T}issue}, volume = 12, year = 2021 }
3. Bleiler, C., Ponte Castañeda, P., & Röhrle, O. (2021). Tangent second-order homogenisation estimates for incompressible hyperelastic composites with fibrous microstructures and anisotropic phases. Journal of the Mechanics and Physics of Solids, 147, 104251. https://doi.org/10.1016/j.jmps.2020.104251
  - BibTeX
  BibTeX
  @article{Bleiler2021, author = {Bleiler, Christian and Ponte Casta{\~{n}}eda, Pedro and R{\"o}hrle, Oliver}, doi = {10.1016/j.jmps.2020.104251}, issn = {0022-5096}, journal = {Journal of the Mechanics and Physics of Solids}, pages = 104251, title = {Tangent second-order homogenisation estimates for incompressible hyperelastic composites with fibrous microstructures and anisotropic phases}, url = {https://doi.org/10.1016/j.jmps.2020.104251}, volume = 147, year = 2021 }
2019
1. Trivedi, Z., Bleiler, C., Wagner, A., & Röhrle, O. (2019). A parametric permeability study for a simplified vertebra based on regular microstructures. Pamm, 19, Article 1.
  - BibTeX
  BibTeX
  @article{trivedi2019parametric, author = {Trivedi, Zubin and Bleiler, Christian and Wagner, Arndt and Röhrle, Oliver}, journal = {PAMM}, number = 1, pages = {e201900383}, title = {A parametric permeability study for a simplified vertebra based on regular microstructures}, volume = 19, year = 2019 }
2. Bleiler, C., Ponte Castañeda, P., & Röhrle, O. (2019). A microstructurally-based, multi-scale, continuum-mechanical model for the passive behaviour of skeletal muscle tissue. Journal of the Mechanical Behavior of Biomedical Materials, 97, 171–186. https://doi.org/10.1016/j.jmbbm.2019.05.012
  - BibTeX
  BibTeX
  @article{bleiler2019microstructurally, author = {Bleiler, Christian and Ponte Casta{\~n}eda, Pedro and R{\"o}hrle, Oliver}, doi = {https://doi.org/10.1016/j.jmbbm.2019.05.012}, journal = {Journal of the Mechanical Behavior of Biomedical Materials}, pages = {171--186}, publisher = {Elsevier}, title = {A microstructurally-based, multi-scale, continuum-mechanical model for the passive behaviour of skeletal muscle tissue}, volume = 97, year = 2019 }
2017
1. Bleiler, C., Ponte Castañeda, P., & Röhrle, O. (2017). A homogenisation method for the multiscale modelling of transversely isotropic skeletal muscle tissue. Pamm, 17, Article 1.
  - BibTeX
  BibTeX
  @article{bleiler2017homogenisation, author = {Bleiler, Christian and Ponte Casta{\~n}eda, Pedro and R{\"o}hrle, Oliver}, journal = {PAMM}, number = 1, pages = {183--184}, publisher = {WILEY-VCH Verlag Berlin}, title = {A homogenisation method for the multiscale modelling of transversely isotropic skeletal muscle tissue}, volume = 17, year = 2017 }
2. Bleiler, C., Ponte Castañeda, P., & Röhrle, O. (2017). A novel microstructurally-based material model to describe passive skeletal muscle tissue. In J. M. Floryan (Ed.), Contributions to the Foundations of Multidisciplinary Research in Mechanics (Vol. 3, pp. 1921–1922). IUTAM.
  - BibTeX
  BibTeX
  @inproceedings{Bleiler2017a, author = {Bleiler, Christian and Ponte Casta{\~{n}}eda, Pedro and R\"ohrle, Oliver}, booktitle = {Contributions to the {F}oundations of {M}ultidisciplinary {R}esearch in {M}echanics}, editor = {Floryan, J. M.}, isbn = {978-0-660-05459-9}, organization = {IUTAM}, pages = {1921-1922}, title = {A novel microstructurally-based material model to describe passive skeletal muscle tissue}, volume = 3, year = 2017 }
2016
1. Heidlauf, T., Klotz, T., Rode, C., Altan, E., Bleiler, C., Siebert, T., & Röhrle, O. (2016). A multi-scale continuum model of skeletal muscle mechanics predicting force enhancement based on actin--titin interaction. Biomechanics and Modeling in Mechanobiology, 15, Article 6. https://doi.org/10.1007/s10237-016-0772-7
  - BibTeX
  BibTeX
  @article{heidlauf2016multi, author = {Heidlauf, Thomas and Klotz, Thomas and Rode, Christian and Altan, Ekin and Bleiler, Christian and Siebert, Tobias and R{\"o}hrle, Oliver}, doi = {https://doi.org/10.1007/s10237-016-0772-7}, journal = {Biomechanics and modeling in mechanobiology}, number = 6, pages = {1423--1437}, publisher = {Springer Berlin Heidelberg}, title = {A multi-scale continuum model of skeletal muscle mechanics predicting force enhancement based on actin--titin interaction}, volume = 15, year = 2016 }
2. Bleiler, C., Ponte Castañeda, P., & Röhrle, O. (2016). Multiscale modelling of skeletal muscle tissue by incorporating microstructural effects. Pamm, 16, Article 1.
  - BibTeX
  BibTeX
  @article{bleiler2016multiscale, author = {Bleiler, Christian and Ponte Casta{\~n}eda, Pedro and R{\"o}hrle, Oliver}, journal = {PAMM}, number = 1, pages = {75--76}, publisher = {WILEY-VCH Verlag Berlin}, title = {Multiscale modelling of skeletal muscle tissue by incorporating microstructural effects}, volume = 16, year = 2016 }
2015
1. Bleiler, C., Wagner, A., Stadelmann, V. A., Windolf, M., Köstler, H., Boger, A., Gueorguiev-Rüegg, B., Ehlers, W., & Röhrle, O. (2015). Multiphasic modelling of bone-cement injection into vertebral cancellous bone. International Journal for Numerical Methods in Biomedical Engineering, 31, Article 1.
  - BibTeX
  BibTeX
  @article{bleiler2015multiphasic, author = {Bleiler, Christian and Wagner, Arndt and Stadelmann, Vincent A and Windolf, Markus and K{\"o}stler, Harald and Boger, Andreas and Gueorguiev-R{\"u}egg, Boyko and Ehlers, Wolfgang and R{\"o}hrle, Oliver}, journal = {International journal for numerical methods in biomedical engineering}, number = 1, title = {Multiphasic modelling of bone-cement injection into vertebral cancellous bone}, volume = 31, year = 2015 }
2. Bleiler, C., Ponte Castañeda, P., & Röhrle, O. (2015). Towards effective mechanical properties of skeletal muscle tissue via homogenisation. Pamm, 15, Article 1.
  - BibTeX
  BibTeX
  @article{bleiler2015towards, author = {Bleiler, Christian and Ponte Casta{\~n}eda, Pedro and R{\"o}hrle, Oliver}, journal = {PAMM}, number = 1, pages = {83--84}, publisher = {WILEY-VCH Verlag Berlin}, title = {Towards effective mechanical properties of skeletal muscle tissue via homogenisation}, volume = 15, year = 2015 }
2014
1. Bleiler, C., Wagner, A., Stadelmann, V., Windolf, M., Gueorguiev-Rüegg, B., Köstler, H., Boger, A., Ehlers, W., & Röhrle, O. (2014). Multiphasic Modelling of the Vertebral Bone for Cement-Injection Studies. Pamm, 14, Article 1.
  - BibTeX
  BibTeX
  @article{bleiler2014multiphasic, author = {Bleiler, Christian and Wagner, Arndt and Stadelmann, Vincent and Windolf, Markus and Gueorguiev-R{\"u}egg, Boyko and K{\"o}stler, Harald and Boger, Andreas and Ehlers, Wolfgang and R{\"o}hrle, Oliver}, journal = {PAMM}, number = 1, pages = {117--118}, publisher = {WILEY-VCH Verlag Berlin}, title = {Multiphasic Modelling of the Vertebral Bone for Cement-Injection Studies}, volume = 14, year = 2014 }

Vita

May 2022 – today: Lecturer/Senior Scientist, Chair for Continuum Biomechanics and Mechanobiology, Institute for Modelling and Simulation of Biomechanical Systems, University of Stuttgart
Apr 2021 – Apr 2022: Research Associate, Chair for Continuum Biomechanics and Mechanobiology, Institute for Modelling and Simulation of Biomechanical Systems
Jun 2019 – Apr 2021: Research Assistant, Chair for Continuum Biomechanics and Mechanobiology, Institute for Modelling and Simulation of Biomechanical Systems
May 2016 – July 2016: Visiting Associate with Prof. Pedro Ponte Castañeda, Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania
Jan 2013 – May 2019: Research Assistant, Continuum Biomechanics and Mechanobiology Research Group, Institute of Applied Mechanics
Nov 2012: Diploma (Dipl.-Ing.) in Civil Engineering at the University of Stuttgart
2007 – 2012: Studies in Civil Engineering at the Universities of Karlsruhe and Stuttgart

Activities in the scientific community

Reviewer for the following scientific journals:

Biomechanics and Modeling in Mechanobiology
Computers, Materials & Continua
European Journal of Mechanics - A/Solids
Frontiers in Physiology
GAMM-Mitteilungen
International Journal for Numerical Methods in Biomedical Engineering
Journal of Psychosomatic Research
Journal of the Mechanical Behavior of Biomedical Materials
Journal of the Mechanics and Physics of Solids
Scientific Reports

Member of the organisation committee of the VPH (virtual physiologcial human) conference 2024 in Stuttgart (conference chairs: Prof. Oliver Röhrle & Prof. Tim Ricken). September 4-6, 2024.

Organisation of conference minisymposia:

Current trends in modelling and simulation of biological systems: numerics, application and data integration, 10^th GACM Colloquium on Computational Mechanics, Vienna, September 10-13, 2023. Jointly organised with Sebastian Brandstaeter, Lena Lambers and Renate Sachse.
Computational biomechanics and biomedical engineering of active biological systems - from methods to clinical application, 9^th GACM Colloquium on Computational Mechanics, Essen, September 21-23, 2022. Jointly organised with Lena Lambers and Renate Sachse.
Numerical methods in biomechanics, 8^th GACM Colloquium on Computational Mechanics, Kassel, August 28-30 2019. Jointly organised with Tillmann Wiegold.

Alumni of CBB from A-Z

B: Dr. Alexandra Brauch (formerly Bayer)
Research Associate from 2009-2016, doctoral examination successfully passed in 2016

H: Prof. Daniel Häufle
Research Associate from 2009-2020

Dr. Maria Hammer
Research Associate from 2011-2025, doctoral examination successfully passed in 2024

Assistant Professor Zhiming Hu
Research Associate from 2023-2025

J: Marc Jakob
Research Associate from 2017-2019

L: Patrick Lerge
Research Associate from 2021-2024

M: Dr. Laura Meszaros-Beller
Research Associate in 2022

N: Fabian Neininger
Research Associate from 2016-2018

Dr.-Ing. Lennart Nölle
Research Associate from 2020-2024, doctoral examination successfully passed in 2024

R: Julia Riede
Research Associate from 2018-2021

Tille Rupp
Research Associate from 2009-2016

S: Mohammadhassan Samadpour
Research Associate 2024-2025

Dr.-Ing. Pablo Santana Chacon
Research Associate 2020-2025, doctoral examination successfully passed in 2025

Johannes Schnaidt
Research associate in 2020

Dr.-Ing. Simon Schwärzli (formerly Wolfen)
Research Associate from 2016-2020, doctoral examination successfully passed in 2023

Katrin Stollenmaier
Research Associate from 2020-2021

W: Dr. Johannes Walter
Research Associate from 2017-2022, doctoral examination successfully passed in 2021

Dr. Isabell Wochner
Research Associate from 2018-2023, doctoral examination successfully passed in 2023

Christian Bleiler

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2026

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2024

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2022

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2021

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2019

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2017

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2016

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Christian Bleiler

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2026

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2024

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2022

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2021

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2019

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2017

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2016

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2015

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2014

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Alumni of CBB from A-Z

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