Contact
Pfaffenwaldring 5a
70569 Stuttgart
Deutschland
Subject
Pouyan's research lies on the interface of biophysics, computer vision and machine learning. He focuses on developing biophysics-aware machine learning models to investigate dynamics of biological processes. His main focus has been investigating structure-function relathionship in nano-scale of biopolymers in cellular proceeses and micro-scale of bone tissue. He has developed biomedical image analysis frameworks include deep learning models for resolving high resolution computer tomogrophy (CT) images and biopolymer structural feature-extraction models from laser confocal scanning microscopy (CLSM) images. Pouyan's current research focuses on developing bone maturation and adaptation deep learning models from time-resolved HR-pQCT and µCT images and simulation based data synthesis.
Surrogate machine learning model of structure-function relationship of biopolymers (Asgharzadeh et al. Acta Bio. 2018 and Asgharzadeh et al. BioRxiv 2020)
Bone aging assesment model (BAAM) deep neural network (Asgharzadeh et al. Acta Bio. 2020)
- Asgharzadeh, Pouyan, Annette I Birkhold, Zubin Trivedi, Bugra Özdemir, Ralf Reski und Oliver Röhrle. 2020. A NanoFE Simulation-based Surrogate Machine Learning Model to Predict Mechanical Functionality of Protein Networks from Live Confocal Imaging. Computational and Structural Biotechnology Journal 18: 2774–2788. doi:https://doi.org/10.1016/j.csbj.2020.09.024, http://www.sciencedirect.com/science/article/pii/S2001037020304086.
- Asgharzadeh, Pouyan, Oliver Röhrle, Bettina M Willie und Annette I Birkhold. 2020. Decoding Rejuvenating Effects of Mechanical Loading on Skeletal Aging using in Vivo microCT Imaging and Deep Learning. Acta Biomaterialia. doi:https://doi.org/10.1016/j.actbio.2020.02.007, .
- Reski, Ralf, Bugra Özdemir, Pouyan Asgharzadeh, Annette Birkhold und Oliver Röhrle. 2019. The plastid skeleton: a source of ideas in the nano range. In: Biomimetics for Architecture. Learning from Nature, 163–166. Birkhäuser.
- Özdemir, Bugra, Pouyan Asgharzadeh, Annette I Birkhold, Stefanie J Mueller, Oliver Röhrle und Ralf Reski. 2018. Cytological analysis and structural quantification of FtsZ1-2 and FtsZ2-1 network characteristics in Physcomitrella patens. Scientific reports 8: 11165. doi:https://doi.org/10.1038/s41598-018-29284-y, .
- Asgharzadeh, Pouyan, Bugra Özdemir, Ralf Reski, Oliver Röhrle und Annette I Birkhold. 2018. Computational 3D imaging to quantify structural components and assembly of protein networks. Acta biomaterialia 69: 206–217. doi:https://doi.org/10.1016/j.actbio.2018.01.020, .
- Asgharzadeh, Pouyan, Bugra Özdemir, Ralf Reski, Annette I Birkhold und Oliver Röhrle. 2018. Feature-based Classification of Protein Networks using Confocal Microscopy Imaging and Machine Learning. PAMM 18: e201800246.
- Asgharzadeh, Pouyan, Bugra Özdemir, Stefanie J Müller, Oliver Röhrle und Ralf Reski. 2016. Analysis of Physcomitrella chloroplasts to reveal adaptation principles leading to structural stability at the nano-scale. In: Biomimetic Research for Architecture and Building Construction, 261–275. Springer, Cham. doi:https://doi.org/10.1007/978-3-319-46374-2_13, .
- Asgharzadeh, Pouyan, Bugra Özdemir, Stefanie J Müller, Ralf Reski und Oliver Röhrle. 2016. Analysis of confocal microscopy image data of Physcomitrella chloroplasts to reveal adaptation principles leading to structural stability at the nanoscale. PAMM 16: 69–70.
- 2019 - 2020: Visiting Researcher, Department of Orthopedic surgery, Faculty of Medicine, McGill University, Montreal, Canada
- 05/2020: PhD in Machine Learning and Data-driven Siumlation Science at Institute for Modelling and Simulation of Biomechanical Systems,University of Stuttgart, Gemrnay
- 06/2016: Master of Science in Computational Mechanics of Materials and Structures at the University of Stuttgart, Germany
- 06/2012: Bachelor of Science in Civil Engineering at Sharif University of Technology, Tehran, Iran